What does elevated eosinophil levels indicateblood. Symptoms and treatment

Content:

  • What are these eosinophils?
  • Causes of increased eosinophils
  • Symptoms of increased eosinophils
  • Diagnostics
  • Treatment of elevated eosinophil levels

With a long cold or cough in the blood test
eosinophils are found to be elevated in an adult. About what
it says? Most likely, a runny nose is allergic. Besides
of this, eosinophilia may indicate other serious
pathologies.

What are these eosinophils?

Эозинофилы — это гранулоцитарные лейкоциты,
formed in bone marrow cells. Eosinophils absorb
immune complex during the occurrence of allergic reactions,
mixed to the site of inflammation or to the damaged tissue. In blood
eosinophils are about an hour, then pass into the tissue.

What do eosinophils mean? They are called so because they are actively
absorb the dye eosin, which is used in the laboratory for
diagnostics. Properties eosinovilov varied. For example, they
participate in the formation of the mammary glands after childbirth. Role
Eosinophils in the body:

  • Absorption of alien cells.
  • The formation of antiparasitic immunity.
  • Absorption and binding of histamines and other mediators
    inflammation.

функции эозинофилов


Increased spinal cord production of eosinophils may
cause immediate allergic reactions (anaphylaxis). So
Thus, eosinophils perform anti-allergenic and pro-allergenic
function. Therefore, an increase in eosinophils is observed during
allergies.

The number of eosinophils in the blood varies throughout the day. In the evening
their number increases by 16%, at night – by 30%. Besides того, у женщин
Estrogens enhance eosinophil synthesis, and progesterone
– decrease. Therefore, in the first half of the cycle, an increased
the number of eosinophils, which gradually decreases after ovulation.

Eos is normal, if their number is within 0.4×109 / l
adult and 0.7 x109 / l in a child, which is 1-5% of the total
white blood cell counts.

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Causes of increased eosinophils

Elevated blood eosinophils may
indicate that the body is in a “state
fight “with allergens.

Causes of eosinophilia:

  • Skin diseases: eczema, ringworm, dermatitis.
  • Allergic reaction: asthma, allergic rhinitis, hay
    fever.
  • Infectious diseases: pneumonia, tuberculosis.
  • Parasitic infections: toxoplasmosis, chlamydia, herpes.
  • Diseases of the digestive tract: ulcers, cirrhosis of the liver.
  • Autoimmune diseases: lupus, rheumatoid arthritis.
  • Oncological tumors.
  • Malignant blood diseases: leukemia, malignant
    anemia.
  • Immunodeficiency state.
  • Diseases of the thyroid gland (hypothyroidism).
  • Hypoxia.
  • Magnesium deficiency in the body.
  • Acceptance of some antibiotics, aspirin, Dimedrol.

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In medicine, the following degrees of increase in eosinophils are distinguished:

  • Easy – less than 10%.
  • Medium – an increase of 10-15%.
  • Heavy – more than 15%. This excess indicates
    oxygen starvation of tissues.

With a strong excess of indicators in the body foci form
inflammations, for example, acute rhinitis, laryngeal edema.

In addition to blood, eosinophils can be detected in urine, sputum,
in the fluid separated from the nasopharynx. This phenomenon is characteristic of
asthma, bronchitis, allergic rhinitis.

A large number of eosinophils is not an independent pathology,
this means that the body is undergoing a strong inflammatory
process that needs to be eliminated. Especially dangerous
raising in children. This may indicate such serious
pathologies like:

  • Hemolytic disease.
  • Злокачественное заболевание blood.
  • Asthma, allergic rhinitis.

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Symptoms of increased eosinophils

Symptoms with elevated eosinophils depend on what appears to be
the root cause of the pathological condition:

Reactive diseases (arthritis) give the following
symptoms:

  • anemia;
  • enlarged spleen;
  • inflammation of the veins, arteries;
  • temperature rise;
  • joint pains;
  • weight loss.

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With parasitic conditions in a patient
are observed:

  • nausea:
  • headache;
  • muscle pain;
  • shortness of breath, cough;
  • swollen lymph nodes;
  • general deterioration.

If the increase is caused by allergic reactions, then
Allergy symptoms are present:

  • rash;
  • itching;
  • puffiness;
  • allergic cough.

In diseases of the gastrointestinal tract, provoked an increase
symptoms are as follows:

  • nausea, vomiting;
  • diarrhea;
  • stomach ache;
  • enlarged liver.

Pulmonary form of eosinophilia is expressed in dry cough,
aggravated at night, loss of appetite, weight loss.

Malignant blood diseases give the following
symptoms:

  • joint pains;
  • itching of the skin;
  • enlarged spleen;
  • causeless cough.

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Diagnostics

When one or more of the above
symptoms should be examined to determine the cause
eosinophilia. To do this, appoint the following tests:

  • Общий анализ мочи и blood. It helps to measure the level
    eosinophil, but put final diagnosis from these tests
    can not.
  • Биохимический анализ blood. The special attention is required by the quantity
    liver enzymes and proteins.
  • Analysis of feces for parasites.
  • Blood test for tumor markers. If they are increased, then it says
    about the malignant process.
  • Ultrasound of the internal organs (liver, gallbladder, thyroid gland,
    malago pelvic organs in women). This allows you to identify pathological
    processes that trigger an increase in eosinophils.
  • X-ray lung bronchoscopy is performed to exclude or
    confirmation of pneumonia, tuberculosis, lung cancer.
  • Using ultrasound of the joints, punctures diagnose arthritis.

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