Transplanted skin rejection defeated

Update: February 2019

Russian scientists were able to create skin integuments that are not
will be rejected after transplanting. The latest development will help
get frozen skin material. In this condition
it can be stored for a long time, forming reserves for the case
operations in an emergency order. But still, the main advantage
skin – no graft rejection reaction.

The most common cause of skin transplants is
burn it damage. Modern surgeons use in practice
Three techniques for moving new skin:

  1. Used donor dried integument. In this case
    transplantation is not final, because tissue is especially fast
    will reject
  2. Use of the dermal matrix (skin flap of a corpse without
    cells, inherently composed of collagen fibers and
    elastin).
  3. Growing new skin from the cells of the same organism. but
    This technique is time consuming and only makes sense when
    the appointment of operations in a planned manner.

New development belongs to FNCC of physical and chemical medicine.
Researchers have achieved growing samples with reduced
immunogenicity. The skin making technique now consists of the following.
stages:

  1. Taking a cell culture from a human donor.
  2. The return of cells to their embryonic state by
    “reprogramming” procedures (scientists are seeking to increase the term
    life of such cells).
  3. Inactivation of genes that are responsible for immunogenicity
    cells.

The development of scientists of the FNCC of physico-chemical medicine should now
be tested in numerous tests. In
if it passes all tests, a single repository will be created
skin. This is expected by the summer of 2017. It is worth the Ministry of Health of the Russian Federation
amend the law “On the circulation of biomedical cell
products ”, surgeons will be entitled to try out new skin
covers for emergency patients.

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