The rate of urine analysis according to Nechyporenko, transcript,how to collect analysis

Update: October 2018

Urine analysis according to Nechyporenko is commonly used in
clinical laboratories because it is simple and
informative study to diagnose
inflammatory processes of the urinary system, especially
hidden This technique was proposed by a Soviet oncologist urologist.
A.Z. Nechiporenko.

The essence of the technique

The analysis is assigned:

  • after detection in the general analysis of blood elevated levels
    leukocytes or red blood cells;
  • in the presence of cylinders in the general analysis of urine;
  • in the pathology of the urinary system;
  • to control the treatment.

In the study in 1 ml of urine shaped elements are determined, and
leukocytes, erythrocytes, cylinders.

  • Leukocytes are the blood cells that are responsible for the immune
    control. An increase in their normal amount always occurs when
    the development of inflammation.
  • Red blood cells are blood cells that transport oxygen to
    organs and tissues. Normally they are not in the urine, they appear in case of serious
    pathology of the urinary organs.
  • Cylinders are protein bodies that form at different
    pathology in the tubules of the kidneys.

Cylinders are classified into:

  • granular resulting from cell lysis of the internal
    tubule walls;
  • hyaline that are formed from primary urine protein, not
    had time to return to the blood;
  • erythrocyte, which are erythrocytes, clogged renal
  • waxy, which are formed from hyaline or granular in
    the result of their long stay in the renal tubule;
  • epithelial – the detached epithelium of the renal tubule.

How to collect urine for Nechiporenko?

Proper analysis is important because it depends on
reliability of the result.

  • A day before the analysis it is worth refraining from coloring products.
    (beetroot, carrot juice), stop eating meat,
    alcohol, carbonated drinks, excess
    сладостей,  кондитерских изделий, нельзя принимать
    antibiotics, antimicrobial and diuretic drugs.
  • If a woman has menstruation on the day of analysis, take it.
    analysis can not, in order to avoid blood in the urine.
  • Night urine is collected for analysis, i.e. this is the first morning
  • Urine is collected in a special industrial container.
    production (plastic laboratory glass) or clean
    glass jar.
  • Wash genitals thoroughly before urinating.
    without hygiene products, soap.
  • Start and finish urination should be in the toilet, in the container
    going average portion.
  • Urine should be delivered to the study within 2 hours,
    since during longer storage it can multiply

How to pass the analysis to the child?

  • Undermine child without soap.
  • Option 1 – fasten around the external genitalia
    мочеприемник и ожидать urination.
  • Option 2 – put the child on the oilcloth and wait when he
    will start writing – substitute the prepared urine
  • You can stimulate urination reflexively: by stroking
    back along the spine (children up to a year) or the inclusion of water in
    crane (children older than a year).
  • Warn the doctor that the entire urine portion has been tested.

Norm during pregnancy

In pregnancy, analysis rates are often close to
maximum allowable. This is due to increased daily
diuresis and does not apply to pathology.


Norms in children and adults are the same. Normal urinalysis
suggests the following indicators:

  • leukocytes: up to 2 thousand in 1 ml;
  • red blood cells: up to 1 thousand in 1 ml;
  • cylinders: up to 20 units of hyaline are allowed in 1 ml. Other
    cylinders in any quantity belong to the pathology.

Poor urinalysis is the excess of the indicated uniform thresholds.
elements, as well as the identification of bacteria, protein or epithelium
(the detection of the last three is noted in the direction of
study). Such an analysis suggests inflammation and other
pathology in the urinary system. However, do not rush to put
self diagnosis – the results of urine analysis according to Nechiporenko has the right
interpret only by the attending physician!

Leukocyte increase
Increase in red blood cells
  • Pyelonephritis
  • Urolithiasis disease
  • Kidney infarction
  • Cystitis
  • Prostatitis
  • Nephrotic syndrome
  • Acute glomerulonephritis
  • Kidney infarction
  • Chronic renal failure
  • Urolithiasis disease
  • Tumor process
  • Purulent cystitis
  • Kidney tuberculosis
Увеличение гиалиновых цилиндров >20
  • Pyelonephritis
  • Hypertonic disease
  • Acute glomerulonephritis
  • Chronic glomerulonephritis
  • Acceptance of diuretic drugs
 Waxy Cylinders  Erythrocyte Cylinders
  • Kidney amyloidosis
  • Nephrotic syndrome
  • Chronic renal failure
  • Malignant Hypertension
  • Renal vein thrombosis
  • Kidney infarction
Epithelial Cylinders  Granular cylinders
  • Tubular necrosis in the acute phase
  • Overdose of drugs that are toxic to the kidneys (salicylates,
    cyclosporine, lithium)
  • Viral infection
  • Poisoning with heavy metals or substances toxic to
    kidneys (ethylene glycol, phenols, pesticides, ether)
  • Pyelonephritis
  • Glomerulonephritis
  • Viral infections
  • Lead poisoning

Автор: врач-гигиенист, эпидемиолог

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