Prednisone during pregnancy: when necessary taking the drug?


  1. Description of Prednisolone
    1. Release form
  2. Features of taking prednisolone in pregnant women
    1. When is prednisolone needed?
    2. How to take prednisolone for pregnant women?
  3. Pregnant Reviews of Prednisolone

Prednisone during pregnancy is used, as a rule, for therapy for miscarriage and a number of other serious diseases that able to adversely affect the development of the baby. At the same time, assigning the drug, doctors always consider the expected benefits for the mother and risks to the fetus. In the prednisolone annotation, pregnancy is indicated as contraindication to taking the drug. Really, the mechanism of action of the drug can affect the course of pregnancy, but in most cases only with prolonged therapy or in high doses.

Description of Prednisolone

The drug refers to glucocorticoids – synthetic substitutes for steroid hormones produced by the cortex adrenal glands. This is a hormonal drug that is pregnant appointed for health reasons, exclusively under control a doctor.

The spectrum of action of the drug is quite wide:

  • antiallergenic;
  • anti-inflammatory;
  • anti-shock;
  • antitoxic.


Due to its high effectiveness, prednisone is not only used in obstetric and gynecological practice in women during pregnancy, but also in other branches of medicine:

  • dermatology;
  • pediatrics
  • neurology;
  • surgery.

The principle of the drug in systemic use lies primarily in its effect on metabolic processes. In particular, the drug:

  • accelerates the breakdown of proteins;
  • increases the rate of assimilation of sodium, water;
  • stimulates the process of glucose formation.

Release form

Currently, the drug in the domestic market is presented in several forms:

  • solution for parenteral administration;
  • pills;
  • ointment for topical application.

The form of the drug used in pregnant women depends on the period, the nuances of the diagnosis and the stage of development of the disease. Most often women in position take prednisolone in tablets, as in in this case, it is possible to obtain a pronounced therapeutic effect and reduce the risk of negative effects on the child.

ampoules with solution

Features of taking prednisolone in pregnant women

In addition to the therapeutic effect, prednisone during pregnancy able to negatively affect the health of the mother and fetus. As in what cases does this happen?

Firstly, the danger of the drug lies in its effect on protein decay rate. Throughout pregnancy protein in the body of the future mother should be enough, since it is the main material for the formation of embryo tissue.

Secondly, an increased amount of glucose in the blood is inevitable increases fat synthesis. During pregnancy, this is fraught with excess weight gain, the development of edema. In addition, prednisolone washes potassium and calcium from the body, which threatens pathologies of the cardiovascular system, the destruction of tooth enamel in a pregnant woman and defects in the skeletal system in the fetus.

Prednisone triggers adrenaline activity, which provokes spasms of blood vessels, hypertension. These conditions are often lead to:

  • fetoplacental insufficiency;
  • fetal malformations;
  • hematopoietic pathologies.

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Among other things, it should be noted that the drug inhibits cell division process. In view of this, prednisolone is categorically it is forbidden to use during pregnancy up to 12 weeks of gestation. It is known that during this period, the laying of systems and fetal organs, suggesting an active process of tissue growth embryo by cell division.


When is prednisolone needed?

It may seem that during the gestation period the drug has only negative effect. This is actually not the case. Listed The above side effects are relevant if long-term therapy is required. AT in case of short courses, the risk of serious complications minimal.

Caution: Prednisone in most cases is prescribed when there is a threat and treatment is required for the mother. To save pregnancy and, if necessary, effects on the fetus optimally use other corticosteroids, for example, dexamethasone. Prednisolone is destroyed in the placenta by more than 50% and becomes not particularly effective, unlike other means.

Prednisone for pregnant womenThe use of prednisone in the period gestation is advisable in diagnosing:

  • risk of childbirth prematurely – the drug stimulates maturation of surfactant – a substance that provides respiratory functions of the fetus;
  • hyperandrogenism – the drug blocks the active production of the hormone testosterone
  • toxic (shock) state – often used once for relief of symptoms;
  • autoimmune diseases – systemic lupus erythematosus, hepatitis, bronchial asthma, antiphospholipid syndrome.

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If a woman has a history of chronic autoimmune diseases or they developed in the process of bearing, there is a chance that antibodies will begin to be produced in the body of the future mother, hostile to the fetus. Prednisolone’s task this situation – blocking the production of antibodies and how result, preservation of pregnancy.

How to take prednisolone for pregnant women?

Prednisolone during gestation is prescribed exclusively by a doctor according to medical indications. He determines the dose of the drug and the timing treatment.

So, when it comes to long-term or supportive care, optimally use the drug in tablets.

Important: take the pill with meals strictly time indicated by the doctor.

Intravenous or intramuscular administration of prednisolone, as usually necessary in emergency situations when it comes to life and death.

Ointment has the least pronounced therapeutic effect. Her prescribed for the treatment of eczema or psoriasis, but permissible use other analogue tools.

Pregnant Reviews of Prednisolone

I started taking prednisolone from the 2nd trimester of pregnancy as prescribed by the doctor. The reason for the therapy with the drug was the diagnosis adrenal insufficiency and excess testosterone in the blood. Also I read a lot about the negative consequences of treatment for the fetus with long-term use. Now I have 27 weeks pregnancy and the baby is all right. It develops according to deadline and absolutely healthy. I believe that if there are specific testimony, then you need to listen to the doctor.

Anna, 26 years old.

I started taking prednisolone at the age of 23 years, when diagnosed with dermatomyositis. The disease is serious and without due The chances of a productive life are minimal. In this case Prednisolone is a true savior that supports a person’s life. After 3 years, I became pregnant, although doctors banned due to the diagnosis. Throughout the entire period I continued to drink tablets in the habitual for self dose. The daughter was born healthy on time with a weight of 2930. Up to her I was worried for 18 years so that the consequences of my illness did not appear or treatment with prednisolone, but the unrest turned out to be in vain.

Maria, 45 years old.

Hormonal drugs, corticosteroids during pregnancy prescribed for specific indications. If in doubt, anxiety, never hesitate to ask the doctor all those who are interested, even silly, in your opinion, questions to make sure that the treatment will be as safe as possible for your baby. Be healthy!

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