- What are neutrophils?
- Neutrophilous rate in children
- Reduced neutrophils in the blood of a child
- What does it mean?
- The reasons
- Neutrophil Reduction Infections
- Congenital diseases
- Why is neutropenia dangerous?
- How to increase neutrophils in the blood?
When a child’s blood counts change, it should
to alert the parents. Seeing a doctor in this case is mandatory,
as a specialist can not only determine the reasons for the decline
neutrophils, but also to prescribe adequate treatment for the situation. Need to
понимать, что низкий уровень нейтрофилов в крови у ребенка
indicates a very low immunity, so act
What are neutrophils?
As part of the blood there is a certain set of cells, and each of them
the view performs its own function. For example, red blood cells
supply oxygen, platelets prevent bleeding,
lymphocytes and leukocytes protect the body from infectious
pathogens. Нейтрофилы — это одна из
leukocyte species. They are designed to resist penetration
fungal and bacterial flora.
Neutrophils are of two types:
- Палочкоядерные — это незрелые молодые клетки,
which ripen over time and acquire the core.
- Сегментоядерные — это «воины» иммунной
systems that destroy harmful microorganisms.
If an acute infectious process occurs in a child’s body,
segmented neutrophils always rise.
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Neutrophilous rate in children
The number of neutrophils in a person’s blood depends on his
- up to 1 year – 16-45%;
- 1-2 years – 28-48%;
- 2-4 years – 32-55%;
- 4-6 years old – 32-58%;
- 6-8 years – 38-60%;
- 8-10 years – 41-60%;
- 10-16 years old – 43-60%;
- over 16 years old – 47-72%.
Be sure to pay attention to the percentage
the ratio of segmented and band
If the number of neutrophils is below the normal limit, this is the state
called neutropenia, and if higher – neutrocytosis.
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Reduced neutrophils in the blood of a child
Neutropenia is accompanied by severe disease,
provoked by an infectious or fungal infection. Immune
the system will not respond correctly to pathogens, and therefore
the child becomes more susceptible to bacterial infections, more often
he has stomatitis and gingivitis. Besides,
may delay psychophysical development.
Neutropenia can occur in mild, moderate and severe form.
Pathology differs in congenital and acquired.
Статья в тему:Symptoms анемии у женщин. Treatments and
Congenital pathology can be expressed in the following forms:
- Синдром «ленивых лейкоцитов» — ребенок с
very early age is systematically confronted with
- Циклическая нейтропения — характер течения
pathology is repetitive, and in most cases combined with
agranulocytosis – a very significant decrease or complete absence
- Синдром Костмана — в плазме крови нет зрелых
forms of neutrophils, signs of pathology appear immediately after
the birth of the baby.
- Family benign neutropenia. In that
case, the clinical picture of the pathology is absent, and some
specific therapy is required.
In the first year of life, the child is most often diagnosed.
chronic benign neutropenia – quantitative
cell composition changes at different times. Concentration
neutrophils can range from low to normal. In most
cases by 3 years, this violation is resolved independently. what
concerns the acquired form of pathology, it is associated with exposure
biological, physical and chemical factors.
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What does it mean?
Low levels of neutrophils in a child’s blood may indicate
- bone marrow reduced their production;
- neutrophils die in large quantities;
- there is a serious illness;
- decreased immunity occurred as a result of health problems
– fungal diseases, rubella, measles, infectious hepatitis.
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The clinical picture of reduced neutrophils in the blood of a child
unconditionally depends on the disease that provoked this
process, most often you can see:
- skin rash;
- increased viral infections;
- elevated or low-grade fever;
- increased heart rate;
- fungal pathologies;
- often repeated colds.
If neutropenia is severe, the child may
to occur fever, intoxication, destructive pneumonia.
Important! If a child often has sinusitis, stomatitis,
there is an increase in lymph nodes, ignore it
can not. These are considered to be the first signs that indicate
development of neutropenia.
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The decrease in the concentration of neutrophils in the blood of a child may have
various causes are viral and fungal diseases, disorders in
the work of the bone marrow, problems with the thyroid gland. Also death
neutrophils can be triggered by prolonged use
antibacterial drugs for pain relief and so
Further. What already it was said, neutropenia, though in rare cases,
but it can still be inborn – the bone marrow does not produce
enough of these blood cells. Also number
neutrophil decreases with anemia, chemical poisoning,
anaphylactic shock, acute form of leukemia.
Important! Sometimes a decrease in neutrophil analysis can be
due to improper blood donation. Distortion of the result may
to be with a strong overexcitation of the baby or if he is tight on the eve
to content ↑Статья в тему:The reasons повышения щелочной фосфатазы в
blood. Symptoms и лечение
Neutrophil Reduction Infections
Infectious diseases that can reduce the number of
blood neutrophils, the following:
- fungal infection;
- viral hepatitis;
- flu and parainfluenza;
- typhoid and paratyphoid fever;
- herpes virus;
- Epstein-Barr virus;
- meningitis, sepsis;
All these pathologies adversely affect the work of the bone marrow,
therefore, neutrophil formation is impaired, and their destruction
structure is accelerating.
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what касается наследованных патологий, они могут провоцировать
the following violations in the number of neutrophils:
- benign forms – cyclical or familial
- malignant forms – Shvakhman-Diamond syndrome, severe
Need to сказать, что врожденная нейтропения у детей — это
редкая патология, к примеру, синдром Швахман-Даймонда
diagnosed with a frequency of 1 case for 10-50 thousand children. how
As a rule, this pathology is detected in a child in the first months of life –
children lag behind in development, eat poorly, suffer from frequent
Another congenital disease that decreases
neutrophil count is Kostman’s syndrome. In that случае
наблюдается блокада созревания сегментоядерных neutrophils.
The most common childhood neutropenia is considered benign.
neutropenia. It is associated with individual features of development.
child, does not carry any health hazards, it passes to
3-5 years without treatment. Diagnose this form of pathology in 6-12
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Why is neutropenia dangerous?
The danger of neutropenia is that pathology may increase
the course of the primary disease. The child may appear
serious purulent lesions of the mucous membranes of the oral cavity,
nose and so on, as well as internal organs, which can lead to
the development of toxic shock. If this situation is ignored, the risk
development of blood poisoning (sepsis) increases, in most
cases of sepsis ends with the death of the child.
What already было сказано, хроническая доброкачественная нейтропения
does not bear danger, and the baby is removed from the dispensary registration in
2-3 years after the diagnosis of pathology.
If neutropenia occurs concurrently with bacterial
infection, neutrophilic leukemia cannot be ruled out, which is very
quickly transformed into leukopenia.
In some cases, if the ailment is severely served by therapy or
associated with frequent severe bronchitis and pneumonia, and
also if a child on the background of neutropenia falls behind in the physical and
mental development, he may be assigned a disability.
Статья в тему:Повышенный уровень базофилов – о чем He speaks?
Symptoms и причины.to content ↑