Is penicillin safe during pregnancy?

Content

  1. General characteristics of the antibiotic
    1. Classification and forms of penicillin
  2. When is penicillin prescribed for pregnant women?
    1. Features of use during pregnancy
    2. Limitations and contraindications
    3. Side effects of antibiotic
  3. Reviews about the drug

Penicillin is one of the oldest broad-spectrum antibiotics. actions. Its discovery at the beginning of the twentieth century was the greatest event in medicine. Thanks to the antibiotic, the opportunity to treat diseases that previously claimed the lives of hundreds of people. Today penicillin is also actively used, including with pregnancy. However, it is prescribed, like all other medical drugs, only for specific indications.

General characteristics of the antibiotic

The drug refers to antibiotics based on a dipeptide formed by acetylserine and dimethylcysteine. Principle its action is based on the inhibition of vitamin and amino acid exchange of pathogenic microorganisms with subsequent destruction cell wall, leading to the death of pathogens bacteria.

The drug is highly effective against:

  • streptococci;
  • pneumococci;
  • gonococci;
  • causative agents of tetanus, diphtheria, anthrax and so Further.

Important: during pregnancy, the safest form of penicillin injections are considered. In this form, the active components are already after 30-60 minutes reach maximum blood concentration and quickly spread to muscles, lungs, joints, while practically not absorbed by the stomach.

The drug is excreted from the body through the kidneys and insignificant degree along with bile. Concentration of this an antibiotic in urine is almost 10 times its total content blood flow.

Classification and forms of penicillin

According to generally accepted systematization, the drug is divided into four subgroups:

  • natural penicillins – novocaine salt benzyl, bicillin-3, – 5;
  • semi-synthetic – oxacillin, ampicillin, amoxicillin;
  • carboxypenicillins – carbenicillin, ticarcillin;
  • cyclic ureidopenicillins – meslocillin, mecillam.

penicillin

An antibiotic is available in two forms:

  • powder for solution for injection;
  • pills.

Attention: the tablet form of penicillin is used extremely rarely, including for pregnant women. Active substances of penicillin tend to break down under the influence of gastric juice. Because of this, the effect of treatment does not occur immediately, but after quite a long period, which in most cases unacceptably.

When is penicillin prescribed for pregnant women?

Penicillin has a pronounced bactericidal, bacteriostatic effect and is a priority antibiotics for treatment:

  • pyelonephritis;
  • bronchitis, tonsillitis, accompanied by purulent lesions;
  • pneumonia;
  • chlamydia;
  • sepsis;
  • STI
  • lymphadenitis;
  • osteomyelitis;
  • meningitis;
  • ENT diseases;
  • eye diseases.

Attention: during pregnancy in the early stages of penicillin, like other antibiotics, prescribed only for health reasons. AT the period of active laying of the main systems and organs of the fetus the effects of drugs, even relatively safe ones, may adversely affect the growth and development of the embryo. Optimally apply penicillin in the 2nd trimester after 20 weeks pregnancy.

Features of use during pregnancy

It is advisable to use an antibiotic in pregnant women conduct allergy tests. A similar procedure is carried out by two ways:

  • a small amount of the drug is dripped artificially a scratch created on the back of your hand with a special pen and observe the reaction;
  • women take blood from a vein and in the laboratory under help reagents investigate the effect of penicillin.

antibiotic powder

If allergies are not identified, the drug is administered intravenously or intramuscularly up to 4 times a day. Exact Dose and Multiplicity the application is determined by the attending physician, taking into account the clinical picture diseases and individual characteristics of the pregnant woman. A solution for parenteral administration is prepared immediately before application. For this, 250 mg of penicillin powder is diluted with 1.5 ml liquids (water, saline).

The average course of treatment is 5-7 days, but may adjusted according to the dynamics of improvements.

About whether penicillin tablets can be given to pregnant women, we already they said. Recall that during gestation this form of the drug banned, as the risk of developing defects is very high.

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Limitations and contraindications

During pregnancy, penicillin is not prescribed in case of detecting a woman allergic to antibiotics or individual components of the drug. Treatment is not recommended for bronchial asthma

drug effectWith renal or liver failure the dose of penicillin is reduced, thereby increasing the elimination period for prevent complications.

In addition, a contraindication to the use of this medicines include the first weeks of pregnancy and the period breastfeeding. Penicillin is excreted in breast milk and penetrates the body of the child, which is fraught with development in the baby diarrhea, thrush, skin rash. Optimally on time antibiotic therapy to stop breastfeeding.

In the second and third trimesters of penicillin during pregnancy as safe as possible for the fetus and for the mother.

Side effects of antibiotic

Penicillin is one of the least toxic antibiotics. Not less drug can cause a number of negative side effects phenomena from different systems and organs:

  • diarrhea;
  • vomiting
  • cramps
  • neurotoxic reactions;
  • coma;
  • increase in body temperature;
  • swelling
  • dysbiosis;
  • candidiasis;
  • bouts of nausea.

If you do not previously carry out a diagnosis in a pregnant woman allergies to penicillin, the risk of anaphylactic increases shock – a generalized rapid allergic reaction.

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For the prevention of dysbiosis during antibiotic therapy it is advisable to take drops or capsules that restore normal intestinal microflora. Drugs are selected by a doctor individually.

Reviews about the drug

During the first pregnancy, I caught pyelonephritis. It’s impossible to convey how scared I was for my baby, but still it became worse when the doctor announced the need antibiotic therapy. I read that taking antibiotics can lead to malformations in the fetus, but the doctor reassured. At that moment I have was 29 weeks, and the doctor assured that penicillin is not capable have a teratogenic effect on the fetus, unlike the disease, which is very dangerous during pregnancy. The treatment helped and, Thank God, the health of the child was not affected.

Eugene, 34 years old.

At the 20th week of pregnancy, I was hospitalized with a diagnosis purulent tonsillitis. Almost immediately, they started injecting penicillin 3 once a day, as the condition was critical. The doctor reassured that on my term antibiotics of a certain group are allowed. In this I made sure after the birth of the baby. There is no disease, no treatment not reflected, which I am very glad. I also want to note that on during therapy I did not feel discomfort and described in the annotation side effects.

Olga, 24 years old.

We hope our article helped you answer the question whether penicillin during pregnancy, and now, if necessary treatment with the drug, you can safely take a balanced, the right decision. Be healthy!

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