- Description and types of thrombophilia
- Causes of Thrombophilia
- General symptoms of the disease in pregnant women
- Diagnosis of thrombophilia
- Gestation Thrombophilia Therapy
- The course of pregnancy on the background of the disease
- How to plan a pregnancy for thrombophilia?
How correctly and fully the baby will develop in the womb depends on many factors. One of the most significant is the quality of uteroplacental circulation. Thanks to a good, uninterrupted blood flow in the system “mother-placenta-fetus” the baby receives all the necessary nutrients substances and oxygen. However, in case of development during pregnancy a disease such as thrombophilia, this process is disrupted. Pathology can provoke serious developmental abnormalities fetus and even cause abortion.
Description and types of thrombophilia
Thrombophilia is a group of pathologies characterized by defects processes of hemostasis, namely increased blood coagulability. It is clear that during childbearing the disease can extremely negatively affect the health of the baby and woman. Yet one danger of pathology is that for a long time you can even not suspect its presence, even surgical interference, serious injury, or pregnancy.
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The development of thrombophilia can be affected as external factors, for example, mechanical damage to blood vessels or surgery, and congenital due to genetic predisposition causes. In the first case, we are talking about acquired thrombophilia. In the second suggests hereditary pathology. Despite various causes of the disease, the consequences of thrombophilia are capable adversely affect the course and completion pregnancy.
Causes of Thrombophilia
In the vast majority of cases in medical practice hereditary thrombophilia is diagnosed when hemostasis disorders due to genetic factors. Pathology is transmitted to the child. from parents, however, can develop against the background of random gene mutations.
In the case of acquired pathology, risk factors may protrude:
- diseases of the circulatory or immune system;
- treatment with aggressive drugs;
- vascular damage, for example, with vasculitis or atherosclerosis;
- inflammatory foci in the body;
- increased physical activity;
- chronic dehydration;
- oncological diseases;
- blood transfusion procedure.
Hereditary thrombophilia due to genetic violations, as a rule, not explainable, and in this case, it is optimal to identify it before conception, in order to pass in advance appropriate treatment and pregnancy further.
General symptoms of the disease in pregnant women
Quite often, thrombophilia can occur completely asymptomatic, being in latent form, until their kind of disease catalysts.
Important: severe symptoms can be observed only with the transition of the disease to a severe stage when urgent treatment.
The rest is the manifestation of thrombophilia during gestation depends on localization, the degree of formation of blood clots, causes and features of the development of pathology. So, to direct or indirect symptoms of both genetic and acquired thrombophilia during pregnancy include:
- swelling of the upper and lower extremities;
- malfunctioning of internal organs;
- cyanosis of the skin;
- general weakness;
- chronic fatigue;
- shortness of breath;
- headaches and stuff.
Quite often, women in position do not attach much importance this symptomatology, attributing it to a special condition or manifestations vegetovascular dystonia syndrome (VVD).
Diagnosis of thrombophilia
Before talking about specific diagnostic methods, denote situations in which the doctor can refer a woman to diagnosis of genetic thrombophilia:
- habitual miscarriage;
- complications in previous pregnancy;
- blood clots due to the use of hormonal contraceptives;
- unsuccessful in vitro fertilization attempts – ECO;
- thrombotic complications in close relatives or directly at the woman herself.
In modern conditions, diagnosing thrombophilia is quite simply. Thanks to a well-chosen combination of analyzes, you can establish not only the presence, degree of disease progression, the type, but also the nature of the mutation of hemostasis genes.
Caution: with acquired thrombophilia, they are often diagnosed antiphospholipid syndrome – APS.
In addition to screening tests blood coagulation – coagulograms, the doctor will study the anamnesis, Paying special attention to the presence in it:
- varicose veins;
- pathologies of gestation;
In the case of confirmation of the diagnosis, the woman is sent to genetics and hematologist. In addition, they conduct a series of specific tests. in several stages for a detailed study of the nuances of pathology.
Gestation Thrombophilia Therapy
If thrombophilia is detected during pregnancy, then treatment appointed promptly in a short time. The course of therapy is selected collegially a hemotologist, gynecologist and geneticist. Habitual scheme treatment, as a rule, includes three main areas:
- drug therapy;
- special diet;
- lifestyle correction.
The medication part involves taking anticoagulants and vitamin complexes selected in each case individually. Make recommendations without knowing the exact diagnosis and anamnesis is incorrect and unprofessional.
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As for diet, it aims to enrich the diet blood clotting products. Here are just some of them:
- fatty fish or fish oil;
- olive, linseed oil;
- natural tomato juice;
- dark chocolate;
- oat groats;
- fresh berries: cherries, cherries, raspberries;
It is also necessary to drink enough water, but in portions, in small sips.
Lifestyle correction involves:
- physiotherapy exercises;
- swimming lesson;
- the use of compression underwear;
- cold and hot shower.
Pregnancy with both hereditary and acquired thrombophilia should be under the strict supervision of doctors. In that case the probability of a successful pregnancy and birth a healthy child is as high as possible.
The course of pregnancy on the background of the disease
Complications of thrombophilia usually begin to manifest after 10 weeks of gestation. Active formation of the placental circle blood circulation increases the load on the general blood circulation system, the risk of thrombosis increases. Early on is great probability:
- missed pregnancy;
- spontaneous abortion;
- pathologies of fetal development incompatible with life.
Important: a diagnosis of thrombophilia in pregnant women involves delivery coagulograms once every 2 weeks or more and regular passage Dopplerography of blood vessels to exclude pathologies of fetal development.
In the future, the probability of complications is noted in the third trimester, after 30 weeks. Due to physiological characteristics blood coagulation is increased to reduce the risk of blood loss in childbirth, however, with thrombophilia this causes additional risks blood clots. Constant monitoring of the condition is required. fetus in order to exclude dangerous pathologies such as:
- fetoplacental insufficiency;
- premature placental abruption;
How to plan a pregnancy for thrombophilia?
Thrombophilia, in which the processes of hemostasis are seriously impaired, not a sentence at all and not a contraindication to pregnancy. The only thing that should be remembered by the expectant mother: she is part of the group risk, which means you need to be as attentive as possible to your health. A prerequisite for a successful pregnancy with thrombophilia is its advance planning and with need treatment.
After carrying out all necessary studies, the doctor in necessarily appoint a woman to take folic acid and vitamin complexes, in which are present polyunsaturated fatty acids. In some cases, shown low molecular weight hyparin (LMWH) as an antithrombotic therapy.
If you are diagnosed with thrombophilia, do not rush to panic and give up the joy of motherhood. Let’s say more: what pathology was detected even before pregnancy, very well. Knowing the diagnosis, you can correctly prepare for the upcoming pregnancy, while maximally eliminating unwanted consequences of thrombophilia during gestation.