Instructions for use of the drugVibrocil

Update: October 2018

Vibrocil – это лекарственный препарат, который широко
appointed by ENT doctors. It has a local vasoconstrictor effect.
and antiallergic effect on the mucous membrane lining
nose. Vibrocil особенно показан при заложенности носа, которую
accompany colds and allergies.

Vibrocil имеет комбинированный состав, который и определяет
therapeutic effect expressed in reducing secretion and
cleansing the nasal passages. It is important that the medicine does not break
physiological, natural functions of the nasal mucosa
cavities.

Фарmgруппа: противоаллергические средства
combined.

Composition, physico-chemical properties, price

Available in 3 dosage forms – gel, drops and spray
nasal, i.e. all forms are applied only topically, on the mucous
the nose.

Main substance Auxiliary components Physical and chemical properties, packaging, price

Dropsвиброцил капли инструкция

In 1 ml of drops: phenylephrine 2.5 mg and dimetinden 0.25 mg

Solution of benzalkonium chloride 50% – 0.2 mg, citric acid – 2.6
mg, sodium hydrogen phosphate – 4.4 mg, sorbitol – 35 mg, lavender oil
– 0.2 mg, water – up to 1 ml

Clear solution with a faint aroma of lavender, colorless or
slightly yellow. Bottles of tinted glass with lid,
supplied with a pipette, packed in cartons.

Price: 220-260 rubles.

Sprayвиброцил спрей применение

In 1 ml of spray: phenylephrine 2.5 mg and dimetinden 0.25 mg

Purified water to 1 ml, sorbitol – 35 mg, sodium hydrogen phosphate
– 4.4 mg, citric acid monohydrate – 2.6 mg, solution
benzalkonium chloride 50% – 0.2 mg (0.1 mg), lavender oil 0.2
mg

Clear solution with a faint aroma of lavender, colorless or
slightly yellow. It is packed in polyethylene bottles with
spray packed in cardboard packs.

Price: 220-250 rubles.

Gelвиброцил гель показания

В 1 гр геля: фенилэфрина 2,5 mg и диметиндена 0,25 mg

Гидрофосфата натрия безводного — 4.4 mg, масла лаванды — 0.2
mg, сорбитола — 35 mg, моногидрата кислоты лимонной — 2.6 mg,
хлорида бензалкония р-р 50%- 0.2 mg, гипромеллозы — 20 mg, воды
очищенная — 935 mg.

Homogeneous gel, colorless or light yellow in color, having
weak aroma of lavender, without foreign particles.

Price: 220-260 rubles.

Vibrocil детский, который допустимо применять у детей с рождения
– this is a form in the form of drops, a separate drug for children
not. Also для детей может быть использован гель и спрей Vibrocil,
but since 6 years old.

pharmachologic effect

The drug has a combined active composition
represented by two substances.

  • Phenylephrine is a sympathomimetic substance that
    has a moderate vasoconstrictor effect when applied topically.
    This effect is due to the stimulation of alpha1-adrenoreceptors,
    which are localized in the nasal mucosa in the venous vessels.
    Phenylephrine quickly eliminates puffiness of both mucous membranes and
    paranasal sinuses.
  • Dimetinden is an anti-allergic substance.
    Antagonist of H1-histamine receptors. Action of dimetinden not
    affects the activity of ciliated epithelium, i.e. does not violate the function
    клеток слизистой the nose.

The combined effect of the two components allows you to quickly clean
nasal passages, eliminate nasal congestion and swelling
mucous membrane.

Pharmacokinetics

Since all dosage forms are applied topically, their
activity does not change with varying concentrations of active
substances in the blood.

Indications

В инструкции по применению Vibrocilа указаны следующие
indications that are the same for all forms:

  • acute (with colds inclusive) and chronic
    rhinitis;
  • allergic rhinitis (including runny nose with hay
    fever);
  • vasomotor rhinitis;
  • chronic and acute sinusitis;
  • acute otitis media (as a subsidiary group drug).

Also назначаются при подготовке к оперативному лечению и для
reduce the swelling of the mucous membranes of the sinuses and the nose, and after
operations in this area.

Vibrocil при гайморите может применяться в качестве
auxiliary drug, in parallel with the antibacterial
treatment.

Contraindications and special instructions

Все формы Vibrocilа противопоказаны при:

  • allergies (hypersensitivity) to dimeinden,
    phenylephrine and auxiliary components;
  • atrophic rhinitis, including the nosological form of ozen;
  • angle-closure glaucoma;
  • simultaneous therapy with MAO inhibitors and another 14 days after
    cancellations;

Dosage forms gel and spray do not apply until 6 years old
age

Patients with CVD diseases (arrhythmia, hypertension,
atherosclerosis generalized), epilepsy, hyperthyroidism, adenoma
prostate, bladder neck blockage, diabetes drug
appointed with caution.

With a pronounced reaction of the body to sympathomimetics, which
manifested insomnia, dizziness, tremor of the hands, arrhythmia,
increasing pressure should also be careful when
применении Vibrocilа.

When drug treatment more than 7 days may develop
the opposite effect (medical rhinitis) when developing
повторная заложенность the nose. Also возможно развитие системного (на
all vessels) vasoconstrictor effect.

Dosage

Before using any of the dosage forms should
thoroughly clear the secret nasal passages.

How many days can you drip Vibrocil? The drug is not prescribed.
more than 7 days. In the absence of a visible effect after
the specified period should consult a doctor.

Nasal drops:

Buried in the nose (in each nasal passage), his head thrown back.
After burying, another 15-20 seconds is kept in the upturned head.
the form.

  • Children up to 12 months: 1 cap. 3-4 r. per day;
  • Children 1-6 years: 1-2 cap. 3-4 r. per day;
  • Children from 6 years old, adults: 3-4 cap. 3-4 r. in days

The number of drops indicated for one nasal passage.

Gel:

Children from 6 years old, adults: the gel is applied deeply, in a small
объеме, в каждый носовой ход, 3-4 раза in days Last application
spend before bedtime, which facilitates the overall condition and provides
therapeutic effect overnight.

Spray:

Spray hold strictly vertically, tip up.
The head is also held straight (not tilted), the tip is inserted
in the nasal passage and in one quick motion squeeze the sprayer, then
take out a tip and unclench a spray. During spraying
for greater efficacy, slightly inhale through the nose. This
dosage form is considered the most effective due to
uniform distribution of the solution in the mucous.

Children 6-12 years old: 1-2 fast sprays in each nasal passage
3-4 раза in days

Side effects

Reactions from the respiratory system are rarely observed.
such as discomfort and dryness in the nose, bleeding from the nose. Also
when applying the gel, there is sometimes a burning sensation in the area of
application. Does not affect the reaction rate when working with mechanisms and
transport management.

With the development of any unusual reactions during treatment
Vibrocilam drug is canceled.

Overdose

Overdose may develop sympathomimetic effects.
in the form of heart palpitations, tremors, increased blood pressure, headache
pain, insomnia, emotional arousal, and pale skin.
Symptomatic treatment.

Drug interactions

Can not be combined with MAO inhibitors (Phenelzin, Iproniazid,
Isocarboxazide and others.), Beta-blockers (Anaprilin,
Vazokardin, etc.), tetra-and tricyclic antidepressants
(Mirzaten, Esprital).

Pregnancy and lactation

In pregnancy, it is not recommended to use Vibrocil in view of
possible general vasoconstrictor action.

Analogs

Analogsчных по составу препаратов на данный момент не
released.

Автор: врач-гигиенист, эпидемиолог

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