Update: February 2019
This statement was made by a group of researchers representing
University of Sheffield (UK), and agreed to
publication of a scientific article in the Molecular Human Reproduction.
According to scientists, they managed to develop a new method for
the study of sperm. Its peculiarity is that now
manipulations of laboratory assistants will not harm spermatozoa. it
significantly improve the accuracy and informativeness of male diagnostics
To date, several methods are already actively used.
study of sperm (see spermogram). However each of
diagnostic methods are detrimental to male germ cells.
There is either the destruction of their cell wall, or “filling”
drug harmful compounds. Sperm, passed one or other
diagnostic steps, no longer suitable for further
IVF (in vitro fertilization). All sperm
remain inactive, unable to fertilize an egg.
In the development of the newest technique, the British needed
conducting a large-scale experiment. They selected a group
subjects consisting of healthy volunteers and men
observed in the clinics of reproductive technology.
Taking from each “fresh” biomaterial (sperm), the scientists placed
it into the centrifuge – an apparatus that allows you to separate the sperm from
the liquid part of the sample. Male reproductive cells were studied with
the help of MRS (magnetic resonance spectroscopy) – methods, not
damaging the cell wall. It is this diagnostic method
reveals pathology only by a change in the biochemistry of cellular
As a result, researchers have found that sperm healthy
men and subjects with infertility are largely different in their
biochemical composition. For example, it differs in content.
glycerophosphocholine, choline, lipids and lactate.
The success of the experiment and its curious outcomes allow us to hope
что вскоре появятся специальные маркеры мужского infertility
Perhaps the MRD is also suitable for diagnosing the causes of infertility in women.
The value of the new technique lies in the fact that it does not
inactivates the sperm cells, therefore, they can be
applied for IVF procedure in the future. Researchers don’t
they rush to draw final conclusions, they need new ones
research to test your hypotheses.