How to treat intestinal dysbiosis: treatmentdiet, drugs

Update: December 2018 When imbalance occurs
obligate beneficial and opportunistic microflora in the intestine,
gastroenterologists according to the results of the analysis of feces, establish the diagnosis
– intestinal dysbiosis, the symptoms of which are expressed in diarrhea,
constipation, nausea, weight loss, in children in occurrence
allergic reactions, anxiety, abdominal pain, etc. How
to treat intestinal dysbiosis? The treatment of this disease should
carried out by a gastroenterologist in several ways:

  • firstly, finding out the causes of dysbacteriosis and their
    elimination. This may be taking antibiotics, food poisoning.
    due to intestinal infection (gastric flu, dysentery,
    salmonellosis), acute or exacerbation of chronic diseases of the gastrointestinal tract
    (cholecystitis, hepatitis, pancreatitis, gastric ulcer), and
    also chronic stress or disturbance in the diet, change
    climate, diet. This is possible through pathogenetic treatment,
    aimed at restoring the intestinal motor functions,
    elimination of inflammatory processes, the appointment of
    enzyme preparations.
  • secondly, the removal of acute manifestations of dysbacteriosis,
    normalization of digestion. In this large positive role plays
    a diet that normalizes bowel activity, this is table number 4, with its
    compliance decreases the intensity of putrefactive processes.
  • thirdly, the correction of the intestinal microflora composition with
    the use of nonabsorbable antibacterial drugs
    bacteriophages, intestinal antiseptics, prebiotics and probiotics,
    restoring normal biocenosis in the intestine (see full
    описание и  Список препаратов пробиотиков).
  • fourthly – strengthening the body’s defenses, application
    plant and synthesized immunomodulators.

Now let’s take a closer look at how to treat intestinal dysbiosis:
drugs, diet with dysbacteriosis, all drugs,
treatment of intestinal dysbiosis:

Treatment of dysbiosis depending on the degree of intensity
violations

The degree of intensity of intestinal microflora disorders
subdivided into 3 groups depending on the age of the patient and
analysis of feces for dysbacteriosis. The table presents
the characteristics of these degrees.

Children under 1 year
  • 1 степень дисбактериоза кишечника —  Снижение количества
    типичных эшерихий до 106-105 КОЕ/г, или
    наоборот их повышение до 109-1010, снижение
    лактобактерий до 105-104, бифидобактерий до
    109-108
  • Grade 2 – Enhancement of hemolytic Escherichia or other
    условно-патогенных микроорганизмов до 105-107
    as well as the possible detection of opportunistic bacteria to
    104-105, снижение лактобактерий до
    104 и менее, бифидобактерий до 108 и
    less.
  • 3 -degree – detection of opportunistic bacteria from
    106-107 и более, при этом снижение
    лактобактерий до 104 и менее, бифидобактерий до
    108 и less.
Children over 1 year old
  • 1 степень — снижение эшерихий до 106-105
    или их повышение до 109-1010, а также
    снижение лактобактерий до 106-105 и
    бифидобактерий до 108–107
  • 2 degree of dysbacteriosis – increase of hemolytic Escherichia or
    условно-патогенных микроорганизмов до 105-107
    или их ассоциаций до 104-105 , при этом
    снижается число лактобактерий до 105 и менее,
    бифидобактерий до 107 и less.
  • 3 степень —  ассоциации условно-патогенных бактерий
    обнаруживаются в количестве 106-107 и более,
    при этом снижаются лактобактерий до 105 и бифидобактерий
    до 107 и less.
Adults under 50
  • Stage 1 – typical Escherichia or reduced to
    106-105 либо повышаются до
    109-1010, лактобактерий снижаются до
    106— 105, бифидобактерий до 107
    106
  • Grade 2 – increase hemolytic Escherichia or other
    условно-патогенных микроорганизмов до 105
    107  или их ассоциации до
    104-105 , при этом снижается число
    лактобактерий до 105 , бифидобактерий до 107
    и less.
  • 3 degree intestinal dysbiosis – association
    условно-патогенных бактерий 106 — 107 и
    более, снижается количество лактобактерий до 105 ,
    бифидобактерий до 107 и less.
Adults over 50 years old
  • 1 степень — типичные эшерихий снижаются до 106
    105 или повышаются до 109— 1010,
    лактобактерий снижаются до 105— 104 и
    бифидобактерии до 107-106
  • Grade 2 – hemolytic Escherichia or other increases
    условно-патогенные микроорганизмы до 105-107
    или их ассоциации увеличиваются до 104— 105,
    лактобактерий падают до 104 и менее, бифидобактерий до
    106 и less.
  • 3 degree – associations of opportunistic bacteria
    увеличиваются до 106-107 и более, а
    лактобактерий снижаются до 104, бифидобактерий до
    106 и less.

When intestinal dysbiosis is detected, treatment in children and
adults depends on the severity of the disease, the main
The principles of therapy are as follows:

With 1 degree of dysbiosis shown:

Диета при дисбактериозе

  • Functional nutrition, vitamin therapy, enterosorbents
  • Prebiotics

With 2 degrees of dysbiosis is recommended:

  • Functional nutrition, vitamin therapy, enterosorbents
  • Probiotics

With 3 degrees of intestinal dysbiosis, treatment with drugs
following:

  • Functional nutrition, vitamin therapy, enterosorbents
  • Antibacterial therapy, bacteriophages, intestinal
    antiseptics
  • Probiotics

Diet for dysbacteriosis – functional nutrition

Как to treat intestinal dysbiosis? With mild imbalance
in the intestinal microflora, it may be enough to eliminate these
reasons with the help of a balanced diet, taking prebiotics or
probiotics. In case of a severe violation simultaneously with the complex
antimicrobial therapy is also shown diet food:

Diet with dysbacteriosis should be balanced in content
fat, protein, and carbohydrate, and also rich in trace elements and 
vitamins, the amount of fluid you drink for an adult should
be at least 2 liters per day. Moreover, it is very good to drink 1-2
glasses of clean water 30-40 minutes before meals, ideally, if
it will be warm mineral water without gases.

It is very important to observe the diet, in accordance with the biorhythms.
human body, that is, food intake is desirable to carry
at the same time – breakfast, 2 breakfast, lunch, afternoon tea and
dinner.

The daily diet of a person with dysbiosis should include
amino acids such as glutamine (a source of high-energy
compounds, nitrogen, purine), arginine, which has
иммуностимулирующий и анаболический эффекты, а также
fermented milk products enriched with active bifidobacteria and
lactobacilli – cottage cheese, kefir, cheese, homemade yogurt, natural
butter. Store butter in our supermarkets
most often contains palm and other refined oils, including
including solid beef tallow, which is very harmful for pancreas
glands and the entire gastrointestinal tract, so you should get a proven or
homemade butter without many additives, or at all
refuse him. Be sure to attend food
fibers and pectins are beets, carrots, bran, cabbage, sea
seaweed.

Not everyone knows that many products are natural.
prebiotics or probiotics, and have a weak antibacterial
action for example for some types of pathogenic microorganisms
the following foods are destructive:

  • E. coli is affected by sweet peppers, onions and pomegranates.
  • On staphylococcus in the intestines – strawberries, raspberries, black chokeberry and
    red rowan, barberry.
  • On Klebsiella, Proteus, Pseudomonas aeruginosa have
    the overwhelming effect of apples, radish, apricot, garlic, sage,
    dill, blueberry, mountain ash, horseradish.
  • Fungi, in particular candidiasis, have a destructive effect.
    lingonberries and fresh carrots.

How to adjust the diet with dysbacteriosis depending on
nature of intestinal pathology:

If feces are dark, offensive

coprogram analysis shows alkaline reaction, mass is not
переваренных волокон  — это гнилостная диспепсия. In that
If necessary, limit fat and meat intake, increase
ration boiled vegetables, cereals, sour milk. Kissel is also useful
or cranberry juice, apricot compotes, dried apricots, fresh apricots.
With this intestinal dysbacteriosis, herbal therapy is based on
the use of wormwood, lemon balm, sage and cumin.

If the feces are yellowish

Yellow feces, in the analysis of acid reaction, a lot of starch and not
переваренной клетчатки-  это бродильная диспепсия. In such
case, you should exclude milk, limit carbohydrates and raw vegetables,
shows more protein foods – cottage cheese, boiled meat, steam
fish, eggs. Vegetables can be eaten only in boiled form, and
well help dairy products and various cereals, such
spices like bay leaf, pepper, cloves inhibit processes
fermentation. From herbal medicine useful herbal teas from chamomile and mint, they
reduce spasms and have anti-inflammatory effects.

If the disease is accompanied by diarrhea

That diet with dysbacteriosis is the use of boiled and
pureed food, and food should be of medium temperature, nor
cold or hot. From phytobalance optimal use
pomegranate crusts, oak bark, compote from the fruits of blueberries, bird cherry.
Read more about all the drugs for diarrhea in our article.

If dysbiosis is characterized by persistent constipation.

Then there should be a lot of fiber in the diet, which in
the maximum amount is contained in apricots, white
cabbage, eggplant, carrots, apples, pumpkin. Improves
intestinal peristalsis compote of rhubarb, as well as pure bran,
which should be taken for 1 hour or art. spoon 3 p / day, perfect
drink this fermented milk product – yogurt, kefir,
bifilinom.

The use of prebiotics for dysbacteriosis

The modern pharmacological industry is very rich
equilibrium medications
intestinal microflora. These drugs include probiotics and
prebiotics, which include either live themselves
microorganisms, or their metabolic products.

To stimulate the natural growth of beneficial bacteria
Gastroenterologists prescribe prebiotics – these are substances entering the
the body along with food of non-microbial origin, they are not
digested, but designed to stimulate the development of normal
microflora because для облигатной, полезной флоры они
serve as a nutrient medium.

Prebiotics не только способствуют улучшению обменной активности
natural microflora, but also inhibit the multiplication of disease-causing
bacteria, the body does not reject them. Unlike probiotics, they do not
нуждаются в особых условиях хранения и  специальной упаковке.
To prebiotics include:

  • Non-digestible disaccharides are Lactulose (Normaze, Duphalac,
    Goodluck, Prelaks, Laktusan), Laktol (Expal), gastrointestinal tract transit
    prebiotic (fructooligosaccharides, artichoke extracts,
    lemon and green tea), lactic acid – Hilak forte.
  • These substances are found in natural products: in cereals –
    corn, chicory, onions and garlic, as well as in dairy
    products.

Treatment of intestinal dysbiosis – probiotic preparations

Probiotics — это препараты для эффективного лечения
intestinal dysbiosis, which include live
microorganisms, they are used for prophylaxis and therapy
dysbiosis, since their action is based on the regulation of microflora
intestine. All probiotics can be divided into several
groups:

Multicomponent

they consist of several types of bacteria, colibacteria,
bifidumbakteriya, lactobacilli is Linex, Bifiform, Bifikol. AT
the average course of treatment of dysbiosis with such drugs is 14
days

Monocomponent

consisting of one type of bacteria – bifidobacteria,
lactobacilli, colibacteria – Bifidumbacterin, Lactobacterin,
Colibacterin. The course of treatment can be from 2 to 4 weeks.

Combined

they include symbiotic communities of major bacteria and
strains that are immune to most antibiotics in
combination with a nutrient medium and immunoglobulin complexes.
These drugs accelerate the growth of beneficial microflora, to them
include Linex, Rioflora immuno, they contain streptococcus,
bifidobacteria, lactobacilli, and bifikol, which contains
E.coli and bifidobacteria.

Recombinant or genetically engineered

besides the obligatory microorganisms they contain cloned
the genes controlling the synthesis of alpha interferon is the bifilis
(бифидобактерии и лизоцин), курс лечения которым до 14 days

Synbiotics

For a more persistent effect, both prebiotics and probiotics are prescribed.
at the same time. For the treatment of intestinal dysbiosis, drugs
Synbiotics are produced with a competent combination of pre- and
probiotics, forming ready-made complex drugs, for example,
Bifidobak, Maltodofilus, Laminolact. The course of treatment is
funds must be at least 21 days.

Antagonists

By probiotics can be conditionally attributed antagonists, this
microorganisms that can also inhibit the development
conditionally pathogenic flora, they include such antidiarrheal
препараты как  Энтерол, Бактиспорин, Бактисубтил. A course of treatment
intestinal dysbiosis with these drugs should not be more than 5-7
days

Read more about all probiotics, analogs of Linex.
here.

However, in severe forms of dysbacteriosis, the use of some
only probiotics and prebiotics are not enough. They are not capable
destroy pathogens since only
compete with the conditionally pathogenic flora, suppressing it
размножение, и в случае серьезного violations равновесия, необходимо
additional use of antibacterial, intestinal
antiseptics.

Antibacterial drugs, кишечные antiseptics,
bacteriophages

Their use should be very careful, appointed only
by a gastroenterologist when the extent and form is known
dysbacteriosis, on the basis of laboratory determined
sensitivity of the bacteria to a particular drug:

Antibacterial drugs

  • Staphylococcus – for example, if dysbacteriosis is caused by reproduction
    staphylococcus, then shows staphylococcal or pyobacteriophage,
    лечение 14 days If it is a combined lesion (inflammation
    the navel of a newborn, the risks of sepsis in premature babies), then macrolides
    (azithromycin, clarithromycin, josamycin) or aminoglycosides.
  • Enterococci – if enterococci prevail (the most common of
    which Klebsiella), then shown Klebsiella bacteriophage or
    nitrofurans (Ersefuril, Furazolidone, Stop diar, Enterofuril),
    macrolides, levomycetin or semi-synthetic penicillins.
  • Protei – modified E. coli or proteus most often.
    sensitive to nitrofuranam – nitrofurans are most effective
    (Ersefuril, Enterofuril), derivatives of nalidixic acid –
    Nevigremon, and also Sulgin, Ftalazol – sulfanamide
    drugs.
  • Pseudomonas aeruginosa – to suppress its reproduction, most often
    используют полимиксин, карбенициллин или аминогликозиды –
    Kanamycin, Gentamicin.
  • Candidiasis – dysbacteriosis caused by the growth of fungi of the genus Candida
    or other fungal agents treated with antifungal drugs,
    such as Fluconazole (Diflucan, Mikosist, Flukozan, Fluconorm and
    Ave), Terbinafin (Lamisil, Terbizil, Terbinoks, Exitern, Bramzil),
    амфотерицин AT (Амбизом, Амфоцил, Амфоглюкамин, Амфолип,
    Fungizon).
  • Clostridia – when it comes to pseudomembranous colitis,
    caused by clostridia, then a course of metronidazole is prescribed first.
    (trichopolum), and its ineffectiveness – antibiotic course
    vancomycin.

Bacteriophages

Bacteriophages, это специальные вирусы, которые действуют на
specific type of bacteria, they can be used as an independent
treatment agent or in combination with other antimicrobial therapy,
use in the form of enemas or for oral administration. Currently
the following bacteriophages are produced: proteic, staphylococcal,
coliprotein and pseudomonas (more about treatment
bacteriophages).

Immunomodulators, vitamins, enterosorbents and other drugs
with intestinal dysbiosis

  • Immunomodulators to accelerate the recovery of microflora
    intestines can be taken only by doctor’s prescription, best
    use herbal preparations such as
    Propolis, Dibazol, Immunal, tincture of echinacea, lemongrass,
    eleutherococcus. No other immunostimulants drugs to take
    without a doctor’s prescription is impossible (see whether drugs are needed to improve
    immunity).
  • Vitamins – during violation of intestinal dysbiosis, absorption and
    the synthesis of vitamins slows down or stops altogether, so when
    long-term intestinal dysbaketrioze, treatment must be supplemented
    taking vitamin complexes in order to avoid
    severe hypovitaminosis, especially deficiency of E, D, A
    of vitamins.
  • Энтеросорбенты – with intestinal dysbiosis, лечение можно
    supplement with the intake of enterosorbents, such as Polysorb, Polifan,
    Activated carbon, Enterosgel, Filtrum STI (instruction).
    However, their use should be short-term, not more than
    7-14  дней и в перерывах между приемом других лекарственных
    means, it is best to take them at night, 1 hour before or after
    2-3 hours after eating and taking other medicines and vitamins
    complexes.
  • Antispasmodics – if the patient is seriously worried about diarrhea, then you can
    in addition to other therapy, to take antispasmodics, such as No-shpa,
    Papaverine, as well as pills for diarrhea – Loperamide, etc., astringent
    herbal fees. If the patient suffers from constipation, then also shown
    antispasmodics and drugs with lactulose, laxatives –
    Forlax, vaseline oil, candles from constipation.
  • Choleretic drugs – immortelle, choleretic fees, Hofitol,
    hepatoprotectors- Carsil, Esentialle, Legalon, Liv 52 (see list
    all drugs for the liver). According to indications may apply
    enzyme preparations – Pancreatin, Mezim, Festal, Creon.
  • Antihistamines – against the background of intestinal dysbiosis in
    children and adults may develop a variety of allergic reactions,
    therefore, it is also possible to use antihistamines,
    allergy pills such as Cetrin, Zyrtec, Zodak, Claritin.
    If the patient develops neurotic conditions,
    take sedatives such as tincture
    Valerian, motherwort.

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