Heart defects – the result of high temperature inpregnant women from 3 to 5 weeks of pregnancy

Update: February 2019

Researchers from the University of Berkeley (California, USA) reported
on opening on its official website: temperature increase in
the first trimester of carrying a child can cause heart defects
and deformities of the facial skull (see first trimester screening).
pregnancy).

These violations of the normal development of the fetus are found
often enough. There are no exact reasons for their development so far, but
previously it was assumed a certain influence of internal factors, to
example, hyperthermia (fever). To date
scientists managed to find molecular mechanisms that explain
congenital abnormalities in newborns.

American researchers have established surveillance of chicken
by zebrafish under the influence of elevated temperatures.
Scientists were able to create a non-invasive technique, which is based on
magnetic interaction. With its help, conditions were recreated
hyperthermia, similar to the human body.

They influenced the neural crest cells – the predecessors
cells that make up the heart and facial skull. Under the influence
elevated temperatures in embryos developed corresponding
vices, for example, Fallot’s tetrad or doubling a hole in the right
the ventricle connecting it to the pulmonary trunk.

It can be concluded that hyperthermia from 3 to 5 week
pregnancy is a factor in the development of defects of the face, jaw and heart
muscle. Therefore, our efforts should be aimed at finding
safe antipyretic drugs for women
awaiting the birth of the baby. After all, there are now
anti-inflammatory drugs (ibuprofen, acetylsalicylic
acid, etc.) are contraindicated when carrying a fetus. Benefit and
the safety of new drugs must exceed the risks from surgeries
correction of malformations in newborns. See also how strong on
Fetal health is affected by stress in a pregnant woman.

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