Glycine: instructions for use for children,adults, the effectiveness and appropriateness of taking, indications andcontraindications

Update: October 2018

Glycine is one of the most popular metabolic
drugs prescribed to improve mental and physical
abilities as well as a sedative and easy
hypnotics in pediatrics and for adult patients.

The action can be both calming and activating in
respect of the central nervous system and varies according to
from the time of taking the drug during the day – this says
instructions for use of glycine.

However, it should immediately focus on the fact that all
препараты-ноотропы без исключения, работают только в
патологически измененных тканях,
улучшая непосредственно
обменные процессы в мозговых клетках при нарушениях, но не
оказывают никакого влияния на здоровую ткань
. I.e
using them to stimulate children’s mental activity,
adults, improve memory and attention (as not rarely recommend) –
if not completely useless, then ineffective (see effect
placebo).

Farmgruppa: A drug to improve brain metabolism.
According to the classification of ATC belongs to the group of nootropes and
psychostimulants.

The composition of the drug, release form, price

  • The active ingredient of the drug is glycine. In 1 tablet of 100 mg
    contains 100 mg of glycine. Tablet Consumables 100
    mg are: 1 mg of magnesium stearate, 1 mg of water soluble
    methylcellulose.
  • Form release: sublingual tablets with a sweetish taste,
    white with marble inclusions, flat cylindrical with
    face forms. In blister packs of 50 sublingual
    tablets in a carton box. Glycine tablets are also available.
    dosage of 150, 400 and 500 mg.

Price: Glycine No. 50 100 mg: 29-36 rubles.

pharmachologic effect

Glycine is the simplest aminoacetic acid. Part of
protein molecules and biologically active compounds. Glycine
is the basis for the synthesis of porphyrins, of which later
синтезируется гемоглобин и миоглобин, а также пуриновых
grounds. It regulates metabolic processes, activates and
normalizes defensive braking reactions in the central nervous system, eliminates
psycho-emotional overstrain, increases cognitive function and
mental capacity. It has alpha1-adrenergic blocking, glycine-
and GABA-ergic, antioxidant and anti-toxic effects.
Glycine регулирует глутаматные рецепторы, за счет чего достигаются
the following drug actions:

  • reducing conflict and aggressiveness;
  • increase the level of social adaptation;
  • improvement and stabilization of mood;
  • speeding up sleep and improving sleep quality (see how fast
    sleep without medication);
  • reducing the severity of vegetative disorders, including
    associated with menopause (see drugs with
    menopause);
  • a decrease in the severity of CNS disorders on the background of a stroke and
    TBI;
  • reducing the toxic effect of ethanol and
    drugs that inhibit the activity of the central nervous system.

Pharmacokinetics – the drug quickly penetrates into the biological
body fluids and tissues, including brain matter. Not
accumulating in tissues, fully metabolized to water and
carbon dioxide.

Indications for use

In the instructions for use of glycine indicated:

  • Decreased performance, mental and physical;
  • Stress and associated psycho-emotional stress;
  • Central nervous system overstrain during a period of increased mental stress
    (exams, etc.);
  • Deviant, contrary to accepted norms, the behavior of
    adolescents and children;
  • Perinatal CNS damage in infants;
  • Ischemic stroke;
  • Organic and functional diseases of the nervous system,
    accompanied by emotional instability high
    excitability, mental decline and impairment
    sleep:

    • neurosis-like states and neuroses
    • vascular dystonia
    • recovery period after TBI (head injuries) and
      neuroinfections
    • perinatal and other types of encephalopathy, including
      alcoholic and narcotic.

This is written in the instructions for glycine, but the first 4 points are not
should be taken seriously. As a result of numerous
studies of the effectiveness of nootropics (including glycine) for
improve mental and physical performance, memory, not
has been proven. Only 1 small glycine study proved
that it has little efficacy in CNS disorders, and
only not in severe cases. For example, in the US, glycine is not used in
these cases (the first 4 points), it is only occasionally used in
psychiatric clinics for the treatment of a number of patients.

Contraindications

Glycine не назначается при наличии индивидуальных реакций
hypersensitivity to the drug and its components.

Glycine беременным и кормящим грудью

It may be applicable for the treatment of these groups of women, but strictly
prescribed by a doctor.

Dosage

Таблетки Glycine предназначены для подъязычного рассасывания.
You can dissolve the drug for the cheek, as well as apply
pre-crushed tablet in powder form.

  • Lesions of the nervous system associated with organic and
    functional changes and occurring with increased
    возбудимостью, изменением эмоционального фона, нарушением sleep:
    Adults take 1 tablet (100 mg) of glycine twice or thrice a day.
    lasting 7-14 days. The course of treatment can be extended to 30.
    days Repeated course application is possible 30 days after
    complete the previous course.
  • Нарушения sleep: по 0,5-1 таблетке за 20 минут да сна.
  • Ischemic cerebral stroke: 1000 mg of the drug is cheek or
    sublingual with 1 tsp water for the first 3-6 hours; on 1000 mg
    per day for the next 1-5 days; further – 1-2 tablets
    glycine three times a day for another 30 days.
  • Encephalopathy, the consequences of an organic lesion of the nervous
    system (central and peripheral): 1 tablet of glycine
    дважды-трижды в сутки длительностью 14-30 days Courses repeat 4-6
    once a year.

Instructions for use of glycine for children

The drug has a sweet taste, so children are usually happy
dissolve pills. When it is impossible resorption pills
(newborns, early childhood) chopping is acceptable
the required amount of the drug in the powder and diluted in tea
a spoonful of water.

  • Children up to three years: 0.5 tab. (50 mg) glycine per reception
    twice or three times a day for 7-14 days, then 50 mg each
    однократно в сутки 7-10 days Daily dose for children up to 3 years
    is 100-150 mg of glycine, and the exchange rate is not more than 2000-2600
    mg.
  • For children over 3 years old, the drug is prescribed in the dosage of adults:
    1 tablet (100 mg) twice or thrice a day for 1-2 weeks,
    with a maximum increase in the course up to 4 weeks.

Side Effects of Glycine

Perhaps the development of hypersensitivity reactions in the form of a rash,
urticaria.

Overdose

Cases of overdose are not described. Possible: reduction
blood pressure, dizziness and nausea.

Drug interactions

When taken simultaneously with drugs from the groups of anxiolytics,
antipsychotics, anticonvulsants, sleeping pills and antidepressants
glycine reduces the severity of side effects first.

special instructions

Wary appointed to persons managing transport
means and busy working with precise mechanisms.

Glycine Analogs

Nootropics also include Piracetam (Nootropil, Piracetam,
Lucetam), Noopept. Among the herbal remedies can be identified Ginkgo
Biloba (Bilobil, Memoplant, Ginkgo Biloba, Tanakan, Ginkoum,
Doppelgerts ginkgo biloba with vitamins gr.V, Vitrum memori),
improves metabolic processes in neurons, as well as enhancing
the effect of nootropic drugs.

В аптечных пунктах можно найти Glycine: Glycine озон, Glycine-Био,
Glycine Эвалар, Glycine Форте, Glycine-Канон.

  • Vita Glycine + Vit. gr.V

100 pieces. 500 mg. 1100 rub.

  • Glycine Эвалар

20 pcs. 50-80 rubles

  • Glycine Форте

50 pcs. 17 rub.

  • Glycine Био

100 mg. 50 pcs. 30 rub

  • Dopellerc glycine (+ Vit. Gr. V)

30 caps 150 rub.

  • Glycine озон
  • Glycine -Канон

Автор: врач-гигиенист, эпидемиолог

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