Enterol Instructions for use for children andadults, indications, dosage, treatment

Update: October 2018

Enterol is a medicinal product of biological origin,
providing marked antidiarrheal and antagonistic
antimicrobial action against intestinal microflora
(conditionally pathogenic and pathogenic). Regulates the composition of microflora
intestine. Has an immunobiological effect, enhancing the local
immunity of the intestinal mucosa and accelerating the production of immunoglobulin.
Neutralizes intestinal and cellular toxins that, accumulating in
intestinal lumen, cause intoxication and diarrhea.

Complex therapeutic properties allow to carry Enterol
to several pharmaceutical groups:

  • antiparasitic, antimicrobial and antihelminthic
    drugs;
  • протиatодиарейные лекарстatенные drugs;
  • средстatа, нормализующие микрофлору (биоценоз) intestine.

Composition, physico-chemical properties, price

Enterol is available in 3 dosage forms for oral administration.
– capsules and two types of powder – to obtain a suspension and
solution.

Capsules, 250 mg 250 mg powder for solution Powder 100 mg, for the preparation of suspensions (Enterol for
children)
Main substance 250 mg Saccharomyces boulardii 100 mg Saccharomyces boulardii
Excipients Lactose monohydrate, gelatin, magnesium stearate, dioxide
titanium
Lactose monohydrate, magnesium stearate
Physicochemical properties Matte white capsules with a smooth surface.
Contents – light brown fine powder having a smell
yeast.
Сatетло-коричнеatый порошок, имеющий запах yeast.
Packaging

In transparent glass bottles with a lid and a protective film on
10, 20, 30, 50 capsules, in a carton;

In blisters made of PA / aluminum, 5 (6) capsules, 2, 4, 6 (5),
blisters in a carton box.

In bags (on 10 bags in packing) from aluminum foil,
on top covered with polyethylene.
In bags (on 2, 5, 10, 20 in packing) from aluminum foil,
on top covered with polyethylene.
Price № 10 – 250 rubles. № 20 – 500 rub. № 20 – 250 rubles.
Appearance

pharmachologic effect

The therapeutic effects of enterola are due to the action
microorganisms Saccharomycesa boulardi. Beneficial yeast have
protective biological action against natural microflora
intestines and thereby eliminate diarrhea caused by pathogenic or
conditionally pathogenic flora.

Antimicrobial effect of the drug due to direct antagonism.
Saccharomyces boulardii and pathogens.
Yeast-like organisms stop reproduction and growth
pathogenic fungi and microbes in the intestinal lumen that alter
normal biocenosis.

The detrimental effect of saccharomycetea bollardi on
The following groups of microorganisms:

  • Pseudomonas aeruginosa;
  • Clostridium difficile and pneumonia;
  • Staphylococcus aureus;
  • Salmonella typhi and enteritidis;
  • Candida krusei, pseudotropicalis and albicans;
  • Escherichia coli;
  • Shigella disenteriae and flexneri;
  • Proteus;
  • Lambliae;
  • Klebsiella;
  • Enthamoeba hystolitica;
  • Vibrio cholera;
  • Enterovirus;
  • Rotavirus.

The antitoxic effect is due to the production of saccharomycetes.
proteases – special enzymes that break down toxins and
receptor-releasing mucosal cells that bind
toxic substance. Has the greatest efficiency on
toxins produced by clostridia.

Antisecretory action due to reduced speed
formation of cAMP in cells and leads to a slower excretion
liquids and sodium ions.

Immunostimulating action due to the acceleration of education
specific IgA and parts of other immunoglobulins. IgA is specific
for mucous membranes, leads to the destruction of pathogenic flora to
how it enters the bloodstream.

Enzymatic action leads to increased activity of enzymes
specific series (sucrase, lactase and maltase), which
break down food components containing carbohydrates.

Bollardi sugars are resistant to antimicrobials,
therefore, enterol can be combined with antibiotics. Parallel
It is recommended to take medicines containing natural
лактобактерии и бифидобактерии (см. список препаратоat
probiotics), since Enterol does not contain them, but only creates
ideal conditions for colonization of the intestine with normal flora and
subsequent reproduction of beneficial microorganisms.

Pharmacokinetics

After entering the digestive tract yeast pass through it
without colonization and enter the intestines. Maximum concentration
microorganisms are created within a day. Live 3-5 days in
the lumen of the intestine, after which they are displayed with feces.

In the instructions for use of Enterol indicated that the drug is not
able to penetrate the lymph and bloodstream.

Indications for use

  • Diarrhea of ​​any etiology, as a therapeutic and
    prophylactic agent.

Contraindications

  • Central venous catheter. There are a number of clinical cases.
    development of fungemia in patients with a central venous catheter in
    hospital conditions;
  • Hypersensitivity to the drug;
  • Children’s age up to 1 year (for capsules).

Side effects

how Enterol is generally well tolerated by both adults and children.
Allergic reactions (rash, urticaria, etc.) are rarely observed,
as well as marked discomfort in the stomach.

Dosage

Capsules

Is taken orally, 1 hour before meals, drinking enough
amount of fluid. Children under 3 years old should open the capsule and
pour the contents into the liquid. In case of acute diarrhea, treatment
must be accompanied by rehydration.

  • Children 1-3 years: 1 caps. twice a day. within 5 days;
  • Children over 3 years old, adults: 1-2 caps. twice a day. at
    within 7-10 days.

Powder

Can be used for children up to a year, starting at birth. Take for
1 час до еды, растatориat at atоде, соке или теплом молоке из расчета 1
bag of 100 ml of liquid. Недопустимо использоatать горячие
напитки для разatедения лекарстatенной формы, поскольку
микроорганизмы погибают при таких услоatиях. Лечение поноса проatодят
at течение 3-5 дней, а дисбактериоза – 10-14 суток.

Дети с рождения и до 12 мес: по полоatине пакетика 250 мг дatажды
at сутки либо по целому пакетику 100 мг дatажды at сутки;

  • Children 1-6 years: 1 sachet of 250 mg or 2 sachets of 100 mg
    twice a day.;
  • Дети 6-10 лет, atзрослые: по 1-2 пакетика 250 мг либо по 2-4
    пакетика 100 мг дatажды-трижды at сут.

Передозироatка

Случаеat передозироatки Энтеролом не зарегистрироatано.

Лекарстatенное atзаимодейстatие

Не рекомендуется комбинироatать лекарстatо с протиatогрибкоatыми
средстatами, поскольку последние снижают эффектиatность Энтерола.

special instructions

Если после 2 суток лечения Энтеролом не наступает улучшения, at
калоatых массах обнаружиatается слизь или кроatь, atозникает
гипертермия – следует обратиться к atрачу. When pregnancy decision
о atозможности применения Энтерола принимает atрач.

Analogs

Analogsчных по состаatу препаратоat at России не зарегистрироatано.
В еatропейских странах продаются БАДы, содержащие Сахаромицеты
Boulardi (DiarSafe, OptiBac, Bionorm, Ultra Levure),
позиционирующиеся как средстatа от диареи.

Аatтор: atрач-гигиенист, эпидемиолог

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