Does “good” cholesterol become “bad”after menopause?

Update: February 2019

The postmenopausal period may affect the protective properties
high density lipoprotein (HDL), better known as
�”Good” cholesterol. This is the conclusion scientists from the School
University of Pittsburgh (University of
Pittsburgh Graduate School of Public Health). Work published in
Arteriosclerosis, Thrombosis, and Vascular Biology.

That high levels of “good” blood cholesterol, along with
normal ratio with other lipids are indicative
healthy vessels and heart, recognized long ago. HDL have
tread action, reduce the deposition of cholesterol plaques on
artery walls, stop the progression of atherosclerosis.
However, a new study found that women after offensive
menopause this protection probably does not extend. results
The works have actualized the question whether it is possible to apply standard
recommendations for determining the risk of cardiovascular pathologies,
include HDL indicators for women after completion
menstruation.

«results работы пригодятся и для врачей, и для простых людей,
because It is the level of HDL that is traditionally estimated at
predicting cardiovascular risk. Doctors should be more
внимательно оценивать данный показатель,  поскольку роль ЛПВП
after menopause may be different from expected. High level
HDL can mask the risk of heart and vascular diseases, ”noted
Samar Hudary (Samar R. El Khoudary), lead author
research.

A group of researchers studied the clinical data 1 138
women in the 45-84 age group who participated in
The Multi-Ethnic Study of Atherosclerosis. It was
found that HDL scores were not reliable
information about the risk of cardiovascular disease in menopause.
Scientists have suggested that reducing the level of estrogen, a hormone with
angioprotective action, along with other age
changes can cause chronic inflammation that changes
effects of “good cholesterol.”

The dangerous association of high cholesterol (HDL) associated with
risk of atherosclerosis was most pronounced in late menopause, and
also in women with a postmenopausal period of at least 10 years. At the age of
perimenopause (years of the strongest hormonal changes) with
risk of developing heart and vascular disease were associated
large particles of HDL. Over time, the protective properties of HDL can
restore. At the same time, the protective properties provided small
HDL particles, as well as their total number.

Co-author of the work, Matthew Badoff from Los Angeles
Institute of Biochemical Research, noted:
the right way to measure good cholesterol
is extremely important for understanding the real state
health of the heart and blood vessels of women in the period of menopause. “

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