Update: October 2018
- Composition, physico-chemical properties, price
- pharmachologic effect
- Indications for use
- special instructions
- Side effects
- Interaction with other drugs
Candles Corilip – a combination drug with pronounced
metabolic and tonic actions due to
unique composition represented by coenzymes and vitamins.
The combination of active ingredients leads to improved exchange
processes in tissues at various physiological and
pathological nature. Available in dosage form for
adults, there are also candles for children (korilip-neo), which
appointed from the neonatal period to 12 months.
Used in cell hypoxia, metabolic acidosis and
other metabolic changes recommended for chronic
intoxications and insufficiency of the liver, kidneys, heart.
Клинико-фармакологическая группа: лекарственное средство
Composition, physico-chemical properties, price
The drug is available in the form of rectal suppositories.
torpedo-shaped, odorless, color – yellow. Are possible
interspersed orange-yellow color.
1 suppository contains (Korilip / Korilip-Neo):
- 25 / 12.5 mg cocarboxylase hydrochloride;
- 2/1 mg riboflavin;
- 12/6 mg of thioctic (α-lipoic) acid.
Auxiliary components: solid fat or cocoa butter (~
The suppositories are placed in the cell contour packages of
polyvinyl chloride film in 5 pieces, in packs of cardboard in 2
Price: № 10: 210-270 rubles.
Restorative effect of the drug is determined by the effects
active substances and their combined action. Cocarboxylase
hydrochloride is a coenzyme that:
- catalyzes carboxylation and decarboxylation reactions
- takes part in carbohydrate metabolism;
- promotes the formation of nucleic acids, proteins, fats,
because takes part in the pentose cycle;
- accelerates tissue metabolism.
Lipoic acid is involved in oxidative
decarboxylation of pyruvic acid and α-keto acids.
It is a regulator of fat and carbohydrate metabolism, directly
takes part in the process of energy formation. It has
hepatoprotective action: protects the tissues of the body from exposure
exo- and endotoxins and improves detoxification function.
Riboflavin is also a coenzyme, is involved in
various metabolic and redox processes
reactions. Plays an important role in the formation of hemoglobin, maintaining
visual function. Normalizes the state of the mucous membranes and
In the instructions for use of Corilip pharmacokinetic data
Indications for use
The drug is prescribed as the main or auxiliary
therapy for certain pathological conditions in children (more often) and
adults, as well as for their prevention.
- chronic tissue hypoxia;
- viral and bacterial infections, including intestinal;
- somatic diseases in chronic form;
- chronic intoxication;
- reduced immunity;
- recovery period after serious illness;
- intense physical and mental stress;
- stressful situations;
- periods of intensive growth and the formation of new skills
In pediatrics and adult practice is prescribed as a tonic
prophylactic during epidemics of infections.
Candles Corilip-Neo is often used in complex therapy in
premature babies and babies born on time but with complicated
period of adaptation.
- Rectal bleeding;
- Hypersensitivity to the drug components
(acting or auxiliary).
With regard to the use of the drug during pregnancy – prescribe
Candles are not recommended since no studies have been conducted.
Meanwhile, there is evidence of the appointment of the drug during pregnancy.
for the relief of severe toxicosis in order to relieve seizures
nausea and improve the general condition of the future mother, which is favorable
affects the course of pregnancy.
The duration of treatment is determined by clinical
status (dynamics) and cytochemical indicators
leukocyte enzyme activity (succinate dehydrogenase and
glycerophosphate dehydrogenase) in peripheral blood.
The drug is a prescription.
Suppositories are used rectally: free from packaging and
gently injected into the anus after defecation.
- Newborns and children up to 12 months.: 1/2 suppositories per day.
- Children 1-6 years: 1 supp. per day.
- Children 6-14 years: 1-2 supp. per day.
- Adults: 1 supp. 2 раза per day.
- Children up to 12 months: 1 supp. per day.
The course duration is 10 days, the total duration
therapy: 3-4 courses with an interval of 20 days.
In rare cases, allergic reactions develop (urticaria,
itching), dyspeptic symptoms and bronchospasm are possible. With the development
any side effects should be discontinued treatment.
Interaction with other drugs
Corilip is often prescribed in combination therapy and is good.
combined with other drugs, including a similar
actions (negative interactions were noted).
Most patients report a positive effect after the course.
therapy, especially in combination with vitamins of group B.
Many women combine Corilip therapy with
rejuvenating treatments and masks and note that the skin
It becomes smooth, clean and healthier.
There are no drugs with a similar composition, but there are
dosage forms containing one of the active ingredients:
Cocarboxylase, Lipoic acid, Berlition, Neyrolipon,
There are a lot of analogues on the therapeutic effect, the most popular ones:
Actovegin, Groprinosin, Immunomax, Polyoxidonium, Cycloferon,
Cerebrum Compositum, Elkar.
Автор: врач-гигиенист, эпидемиолог