Chlamydia treatment – drugs, treatment regimenschlamydia

Update: November 2018

На сегоof the dayшний день проблема лечения chlamydia для многих
It is very difficult for doctors and patients because
often after antimicrobial therapy through a certain
time again manifests this cunning
diseases.

The problem is that most patients register
chronic urogenital chlamydia, whose drug treatment
quite often ineffective.

В чем опасность chlamydia?

Chlamydia trachomatis (Chlamydia trachomatis) most often
causes the following pathologies of the urogenital tract:

  • urethritis in men and women (over half of all non-gonococcal
    urethritis)
  • prostatitis and orchieepididymitis in men, cervicitis, salpingitis,
    endometritis,
  • often combined organ lesions are also observed (for example,
    urethritis, arthritis and conjunctivitis in Reiter’s syndrome program).

At the same time there is a rather lengthy list of laboratory
методов диагностики chlamydia, хотя наиболее достоверными методами
today recognized methods of immunoassay with
monoclonal antibodies (venous blood is used) and
PCR-diagnostics (often scrapings of the urogenital endothelium
tract).

In the treatment of chlamydial infection, as well as the attraction of others
infectious processes in the first place are the tasks of eradication
pathogen and getting rid of acute or chronic inflammation
genitalia and urinary tract, which reduces the quality of life.
Цель по снижению смертности от chlamydia, по счастью перед
a urologist, gynecologist or venereologist is not worth it, because to die from
chlamydial infection of the urogenital tract is very
problematic.

Intermediate goal can be considered to avoid chronic
chlamydia, снижение числа рецидивов хронического хламидийного
process, as well as reducing the number of articular and eye complications
урогенитального chlamydia. You can talk about the desire to reduce
число осложненных или невыношенных беременностей на фоне chlamydia
and the avoidance of post-Chlamydia infertility in both women and women.
men.

Выбор препаратов при лечении chlamydia

With an active inflammatory process, a whole complex is required.
лекарственных средств для полноценного курса лечения chlamydia.
The drugs used in treatment regimens are selected by a doctor with
taking into account the individual characteristics of the patient’s body, clinical
symptoms of the disease, the severity of the inflammatory process and
the results of all tests – immunograms, liver samples, total
blood test, urine culture, results of PCR, ELISA, etc.
laboratory data.

Currently, treatment standards do not imply administration.
immunostimulants or immunomodulators in the treatment of even
осложненного chlamydia. The preparations of these groups, except
serious cytotoxic drugs with strict indications and
appointed only after performing the immunogram, should not
used as drugs with unproven effects. Shamanism
a large number of urologists, venerolgovs or gynecologists in this
areas are more often explained by bonuses from pharmaceutical representatives or
an attempt to lengthen and raise the cost of treatment for patients with paid clinics
and medical centers.

All information about drugs and treatment regimens
intended for review. Лечение chlamydia назначается
only by a qualified physician based on test results, given
patient history, comorbidities, etc.

Read also on the topic:

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  • Chlamydia in women – symptoms, treatment
  • Antifungal drugs in pills
  • Chlamydia in men – symptoms, treatment
  • Antifungal drugs in gynecology
  • 11 rules – How to take antibiotics correctly
  • Burning and pain when urinating in women and men

Chlamydia eradication tactics

Eradication is essentially ridding the body of infectious
agent. Chlamydia is intracellular resident, which can besides
its main form to exist in the L-variant (vegetative), not
capable without significant suppression of host immunity
out of the cage and breeding escaping
antibacterial or phthisic effects (increase
temperature). Chlamydia is best done with
preparations of three antibacterial groups: tetracyclines, macrolides and
fluoroquinolones.

It is worth noting that before starting therapy, chlamydial seeding
cultures for determining sensitivity to antibiotics are not
It’s worthwhile, since the 2000 studies on
bases Research Institute of Obstetrics and Gynecology. D.O. Otta RAMS,
St. Petersburg, Institute of Physico-Chemical Medicine, Ministry of Health of Russia,
Moscow, Institute of Clinical Bacteriology Uppsala
University, Sweden, have shown that resistant in laboratory
conditions, the strains maintained their sensitivity to antibiotics in
the patient’s body.

Антибиотики  при хламидиозе

Antimicrobial agents are essential to the treatment regimen.
chlamydia. And as a rule, in chronic chlamydia treatment
drugs is to use a combination of 2 antibiotics.
Duration of treatment, individual dosage determined by
attending physician depending on the type of disease, the dynamics
inflammatory process.

When choosing an antibiotic for chlamydia are irreplaceable
laboratory data to determine the sensitivity of pathogenic
microorganism to a specific antibacterial drug. therefore
appropriate cultural methods of laboratory diagnosis
supplement with an antibiotic.

Drug name Схема лечения chlamydia

Tetracyclines

Doxycycline (Unidox Solutab, Dorix, Vibramitsin, Vibra-Tabs).
Form solyutab increases the bioavailability of the drug (that is,
its penetration to the tissues) up to 93%.

0.1 twice a day 7 days.

Macrolides

Erythromycin (Erythrocin) – allowed for pregnant and lactating 500 мг 4 раза в сутки через 6 часов, 7  days
Azithromycin (Sumamed, Zitromaks, Hemomitsin) 500 mg 2 tablets. once
Josamycin (Vilprafen) and Clarithromycin (Clarbact, Fromilid
Uno)
750 mg 3 times a day after 8 hours 7 days
Spiramycin (rovamycin) 3 million Units after 8 hours 3 times a day, 7 days

Fluoroquinolones

Ofloxacin (Floxin, Zanotsin, Tarivid, Ofloksin) 300 mg twice a day in 12 hours, for 7 days
Levofloxacin (Tavanic, Glevo, Levostar, Flexid) 1 p / day after meals, 500 mg 1 time per day for 10-14 days,
with complicated forms for more than 14 days.
Lomefloxacin (Lomfloks) 400 mg / day for 10 days.
Sparfloxacin (Sparflo) 200 mg on the first day twice, the second on 1 tablet
Tsiprofloksatsin (Tsifran, tsiprobay, tsiprinol, Tsipro-bid) 2 p / day 500 mg during the week
Norfloxacin (Nolitsin, norbaktin) 2 p / day 400 mg. within 7-10 days;

In practice, preference is given to:

  • 15-membered macrolides, i.e. Azithromycin
  • 16-membered macrolides, i.e., Josamycin,
  • но резистентные формы chlamydia особенно хронического лечат
    fluoroquinolones.

But it will be second-line therapy, as the fluoroquinolones immediately
it is undesirable to prescribe, remembering that soon tuberculosis will be treated
nothing. And fluoroquinolones are reserve drugs. And commercial
the benefit should not blind the eyes, and if it can be treated with a macrolide,
it must be treated with macrolide. In pregnant women permitted drug on
today is josamycin (vilprafen), which is preferred
European standards.

  • Схемы: Азитромицин 500 mg 2 tablets. once, Доксициклин 0,1
    twice a day, 7 days.
  • Second row:
    • Erythromycin 500 mg 4 times a day after 6 hours 7 
      days
    • Ofloxacin 300 mg twice a day in 12 hours for 7 days
    • Roxithromycin 150 mg twice a day after 12 hours 7 days
    • Spiramycin 3 million IU every 8 hours, 7 days
  • For pregnant:
    • Erythromycin 500 mg after 6 hours 4 times a day 7 days
    • Джозамицин 750 mg 3 times a day after 8 hours 7 days,
      Spiramycin 3 million Units after 8 hours 3 times a day 7 days

Both partners are treated. In this case, tetracyclines can
used to treat acute uncomplicated urethritis or
cervicitis in previously untreated patients. Resistant to one of
tetracycline strains of chlamydia are resistant to other
drugs of this group, that is, to change drugs one for another when
inefficiency within the same group makes no sense.

The criterion for cure is negative PCR scraping
urogenital tract 1.5-2 months after the end
therapy.

Probiotics

In order to prevent antibiotic-associated diarrhea and
дисбактериоза кишечника, после лечения chlamydia рекомендуется
take probiotic preparations (see all probiotics – list
drugs with prices and composition).

Probiotics
Drug name Схема лечения chlamydia
Bifikol 5 doses of 3 r / day for half an hour before meals for 14-21
of the day
Lactobacterin 5 doses of 3 r / day for half an hour before meals for 14-21
of the day
Bifidobacterin 5 doses of 3 r / day for half an hour before meals for 14-21
of the day

Once again we remind you that prescribing a course of therapy is only treating
doctor, self-diagnosis and self-treatment are not allowed, it can
harm your health.

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