Causes of diabetes first and secondlike

Update: November 2018

Many diabetics are surprised – why did sugar appear?
I have diabetes? Several chronic endocrine diseases
people in medicine are united under one name – sugar
diabetes.

The causes of this disease is quite a lot, based on
which is a common dysfunction of the endocrine system
based on either an insulin deficiency hormone,
produced by the pancreas, or on the inability of the liver
and body tissues in the proper amount to process and absorb
glucose. Due to the lack of this hormone in the body constantly
the concentration of glucose in the blood rises, which leads to
metabolic imbalance because insulin performs an important
function to control the processing of glucose in all cells and tissues
organism.

When pancreatic tissue is destroyed, cells are destroyed,
responsible for producing insulin, which is the reason
diabetes, as well as if for other reasons changes
sensitivity of cells and tissues of the body to insulin,
contained in human blood.

Types of diabetes

The causes of this disease are in violation
metabolism in the body, namely carbohydrates, as well as fat. AT
depending on relative or absolute insufficiency
insulin production or deterioration of tissue sensitivity to
инсулину, выделяют два основных like диабета и прочие виды:

  • Инсулинозависимый сахарный диабет — 1 like, причины
    occurrences are associated with insulin deficiency. With this type of sugar
    diabetes lack of a hormone leads to the fact that it lacks even
    for processing a small amount in the body
    glucose. As a consequence, blood sugar levels in humans
    rises. To avoid ketoacidosis – increase in urine
    quantities of ketone bodies, patients are forced to constantly drive into
    blood insulin to live.
  • Инсулинонезависимый сахарный диабет — 2 like, причины его
    appearances are rooted in loss of tissue sensitivity to the hormone
    pancreas. With this type there is insulin resistance.
    (insensitivity or decreased tissue sensitivity to
    insulin), and its relative disadvantage. Therefore, it is not uncommon
    hypoglycemic tablets combined with the introduction of insulin.

Сахарный диабет причины возникновенияAccording to statistics
the number of patients with this type of diabetes is significantly greater than 1
type, about 4 times, they do not need additional
insulin injections, and for their treatment used medicinal
pancreatic stimulants for insulin secretion or
reduce tissue resistance to this hormone. Type 2 diabetes
the turn is subdivided into:

  • occurs in people of normal weight
  • appears in overweight people.

Gestational diabetes is a rare type of diabetes that
occurs in women during pregnancy, it develops due to
reduce the sensitivity of a woman’s own tissues to insulin under
the influence of pregnancy hormones.

Diabetes, the occurrence of which is associated with a deficiency
power supply.

Other types of diabetes are secondary because
occur when the following provoking factors:

  • Pancreatic diseases – hemochromatosis, chronic
    панкреатит, муковисцидоз,  панкреатектомия (это диабет 3 like,
    which do not recognize in time)
  • eating disorder leading to a mixed state –
    tropical diabetes
  • Endocrine, hormonal disorders – glucagonoma, syndrome
    Cushing, pheochromocytoma, acromegaly, primary aldosteronism
  • Chemical diabetes – occurs while taking hormonal
    препаратов, психотропных или гипотензивных средств,
    thiazide-containing diuretics (glucocorticoids, diazoxide, thiazides,
    thyroid hormones, dilantin, nicotinic acid, blockers,
    interferon, vakor, pentamidine, etc.)
  • BUTномальность рецепторов инсулина или генетические синдромы
    —  мышечная дистрофия, гиперлипидемия, хорея Гентингтона.

Impaired glucose tolerance, intermittent complex
symptoms that most often go away on their own. it
determined by analysis 2 hours after the glucose load, in
In this case, the patient’s sugar level ranges from 7.8 to 11.1.
mmol / l. При толерантности натощаковыей сахар — от 6,8 до 10
mmol / l, and after eating the same from 7.8 to 11.

Также по теме:

  • Signs of Diabetes
  • Symptoms of diabetes in men

According to statistics, diabetes affects about 6%.
the entire population of the country, it is only according to official figures, but
the real amount is of course much more since it is known
что диабет 2 like может развиваться годами в скрытой форме и иметь
minor symptoms or go completely unnoticed.

Diabetes mellitus is quite a serious disease, because it is dangerous
those complications that develop in the future. By
diabetes statistics, more than half of diabetics die from

angiopathies of the legs, heart attack, nephropathy. Every year over a million
people are left without a leg, and 700 thousand people lose their sight.

Причины возникновения сахарного диабета 1 like

Many are interested in whether to get diabetes?
There is no doubt that diabetes cannot be infected because it is not
infection. It has long been established by experts
that diabetes is most often due to genetic defects,
obesity, autoimmune disorders. So why diabetes
does a person have?

  • The causes of type 1 diabetes mellitus are caused more often.
    total autoimmune processes in which the body
    antibodies against their own cells are produced, the number
    insulin decreases up to complete cessation of production
    hormone. This is a genetic predisposition.
  • According to many doctors, the most likely factor affecting
    извне на развитие  сахарного диабета, считается вирусная
    infection because often after mumps (mumps),
    инфекционного мононуклеоза, краснухи или острого или
    chronic viral hepatitis, the patient is registered sugar
    diabetes. This is because both in healthy people and in patients
    pancreatitis, as well as malignant neoplasms
    pancreatic-like autoimmune processes (antibodies to
    beta cells) are found extremely rarely – 0.3% of cases. BUT
    here the formation of such antibodies appears in patients after
    damage to the beta cells of the pancreas in the background of a viral infection.
    Also modern endocrinology believes that feeding
    cow and goat milk leads to early debut
    diabetes, it is not recommended to give children and fish oil.
  • The development of this type of diabetes mellitus is increased
    T-killer cell activity, that is, not only the violation
    humoral, but also cellular immunity lead to this
    disease.

It is a viral infection that triggers development.
diabetes in children. For example, as a complication after rubella,
every fifth patient after illness develops sugar
type 1 diabetes.

Causes of type 2 diabetes

In this type of diabetes, insulin secretion by beta cells
pancreas remains unchanged, or decreases, but not
much. The bulk of patients with insulin-independent type
diabetes are obese people with a small amount of lean body mass and
a large mass fraction of fat, as well as elderly people. Have
Such diabetes mellitus is considered to be a cause of
the amount of insulin receptors as well
недостаток внутриклеточных ферментов, приводящий к нарушению
exchange of glucose in the cells and tissues of the body. Haveстойчивость
peripheral tissue to pancreatic hormone – insulin
leads to insulinism (increased insulin secretion), which also
promotes

Why does diabetes appear?

Hereditary disposition. With diabetes mellitus in both
parents the risk of developing this disease in children during
жизни гарантирован почти на 60%, если диабетом страдает только
one parent, the probability is also high and is 30%. it
due to hereditary over-sensitivity to
endogenous enkephalin, enhances insulin secretion.

In type 2 diabetes, neither autoimmune diseases nor
viral infection are not the causes of its development.

Frequent overeating, overweight, obesity – are major
causes of type 2 diabetes. Fatty tissue receptors,
в отличие от мышечной,  имеют заниженную чувствительность к
insulin, so its excess affects the increase in the rate of glucose
in blood. According to statistics, if body weight exceeds the norm by 50%, then
the risk of developing diabetes is approaching 70% if overweight
is 20% of the norm, the risk is 30%. However, even with
a normal weight a person can have diabetes, and in
an average of 8% of the population with no weight problems in one way or another
degrees suffer from this affliction.

With overweight, if you reduce body weight, even by 10%
significantly reduces the risk of type 2 diabetes.
Sometimes when losing weight in a diabetic patient – glucose metabolism disorders
either significantly reduced or completely disappear.

Risk factors for diabetes

  • As already mentioned, with genetic disposition, with
    the presence of diabetes in next of kin, the risk of
    diabetes is very high.
  • With significant injury, shock, damage to the pancreas
    glands may also develop diabetes.
  • Overweight, obesity, lack of exercise, lack of
    muscle and abundance of fat body mass.
  • Diseases of the pancreas, accompanied by a lesion
    beta cells.
  • Chronic stress, nervous breakdowns, aggravating factors,
    contributing to the progression of the disease and are starting
    mechanism of onset of the disease with hereditary location and
    overweight.
  • Viral infections such as chickenpox, rubella, hepatitis,
    mumps are provoking factors for people with genetic
    location.
  • Age also plays a key role in the development of diabetes than
    an older person, the more worn the body, there are many
    chronic diseases – all this increases the risk of developing diabetes.
    ATысока вероятность  возникновения заболевания у людей после 45
    years and more it is higher after 65 years.
  • Hypertension, high blood pressure, elevated levels
    fats (triglycerides) in the blood, the use of large quantities
    fatty foods.
  • There is a myth that the more a person uses white
    sugar, so he has a higher risk of diabetes. it не совсем
    so, sweet tooth does not have a higher risk of acquiring this
    diseases only because they eat a lot of sweets. Just u
    they increase the likelihood of overweight, which in its
    queue provokes diabetes, and not vice versa.
  • Most often in the event of diabetes mellitus causes
    turn out to be several at once, it may be heredity, and
    age and overweight.

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